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Type 2 diabetes


08-24-2020 | Glycemic control | News

Multiple factors linked to type 2 diabetes glycemic progression

Extremes of bodyweight and high glycated hemoglobin levels were two of the factors linked to rapid glycemic progression in a study of more than 7000 Chinese people with type 2 diabetes.

05-06-2020 | Genetics | Highlight | News

Genetic markers of type 2 diabetes risk in East Asian people uncovered

A major genetic analysis sheds light on the similarities and differences in type 2 diabetes pathogenesis between people of East Asian and European origin.

04-22-2020 | Depression | News

Genetics casts doubt on bidirectional depression, diabetes association

A Mendelian randomization analysis supports a direct effect of major depressive disorder on type 2 diabetes risk, but produces no evidence for the reverse scenario.

02-17-2020 | Genetics | News

Genetics may contribute to risk for type 2 diabetes after gestational diabetes

Risk alleles for type 2 diabetes influence the risk for women developing the condition after experiencing gestational diabetes, say researchers.

08-01-2019 | Diet | News

Genetics no barrier to dietary modification benefits on type 2 diabetes risk

Genetics and dietary fat each influence people’s risk for developing type 2 diabetes, but without any interaction between the two, show the findings of an individual participant data meta-analysis.

06-08-2019 | Monogenic diabetes | ADA 2019 | News

Monogenic diabetes mutations prevalent in type 2 diabetes

People with type 2 diabetes have a high prevalence of pathogenic mutations in genes typically associated with monogenic diabetes.

05-22-2019 | Genetics | Highlight | News

Exome-wide sequencing study sheds light on type 2 diabetes

Researchers have used exome-wide sequencing to identify several rare variants within four genes that are significantly associated with type 2 diabetes.

12-07-2018 | Pathogenesis | Review | Article

Melatonin in type 2 diabetes mellitus and obesity

Katamitri A, Jockers R. Nat Rev Endocrinol 2018. doi: 10.1038/s41574-018-0130-1

10-15-2018 | Genetics | News

SGLT1 haplotype linked to reduced cardiometabolic risk

Researchers have identified a haplotype of three missense mutations in the sodium-glucose cotransporter-1 gene that is associated with a reduced risk for impaired glucose tolerance, diabetes, and obesity.

09-30-2018 | UKPDS | At a glance | Article

What we learned from the UKPDS

The UKPDS has so far generated an astonishing 93 original research papers. medwireNews​​​​​​​ rounds them up.

07-05-2018 | Lifestyle interventions | News

Healthy lifestyle combats cardiometabolic risk regardless of genetic risk

A healthy lifestyle bestows the same degree of relative risk reduction for type 2 diabetes irrespective of whether people have high or low genetic risk for the condition, shows an analysis of UK Biobank data.

06-25-2018 | Cardiovascular disorders | Review | Article

Shared genetic contribution of type 2 diabetes and cardiovascular disease: Implications for prognosis and treatment

Strawbridge RJ, van Zuydam NR. Curr Diab Rep 2018; 18: 59. doi: 10.1007/s11892-018-1021-5

06-21-2018 | Genetics | Review | Article

Impact of genetic determinants of HbA1c on type 2 diabetes risk and diagnosis

Sarnowski C, Hivert MF. Curr Diab Rep 2018; 18: 52. doi: 10.1007/s11892-018-1022-4

06-21-2018 | Pathophysiology | Review | Article

The gut microbiome as a target for the treatment of type 2 diabetes

Aydin Ö, Nieuwdorp M, Gerdes V. Curr Diab Rep 2018; 18: 55. doi: 10.1007/s11892-018-1020-6

05-19-2018 | Risk factors | Review | Article

Prioritising risk factors for type 2 diabetes: Causal inference through genetic approaches

Wittemans LBL, Lotta LA, Langenberg C. Curr Diab Rep 2018; 18: 40. doi: 10.1007/s11892-018-1009-1

05-09-2018 | Sleep apnea | Review | Article

Maternal non-glycemic contributors to fetal growth in obesity and gestational diabetes: Spotlight on lipids

Barbour LA, Hernandez TL. Curr Diab Rep 2018; 18: 37. doi: 10.1007/s11892-018-1008-2

05-02-2018 | Type 2 diabetes | Article

Association of vitamin D with risk of type 2 diabetes: A Mendelian randomisation study in European and Chinese adults

Lu L et al. PLOS Med 2018; 15: e1002566. doi: 10.1371/journal.pmed.1002566

03-27-2018 | Latent autoimmune diabetes of adulthood | Article

Overweight, obesity, and the risk of LADA: Results from a Swedish case–control study and the Norwegian HUNT Study

Hjort R et al. Diabetologia 2018; 61: 1333–1343. doi: 10.1007/s00125-018-4596-0

10-23-2017 | Diabetes prevention | Review | Article

Reversing the tide: Diagnosis and prevention of T2DM in populations of African descent

​​​​​​​Nat Rev Endocrinol 2017; 14: 45–56. doi: 10.1038/nrendo.2017.127

09-25-2017 | Genetics | News

Genetic variants may impact HbA1c diagnostic threshold in African Americans

Ancestral differences in the impact genetic variants have on glycated hemoglobin can substantially affect the performance of HbA1c as a diagnostic test for type 2 diabetes, results of a large trans-ethnic genome-wide meta-analysis show.

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