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Type 2 diabetes

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a premier resource for the latest clinical information in medicine.

Journal article

The optimal blood pressure target in diabetes mellitus: A quest coming to an end?

Nurse measuring blood pressure (symbolic image with models)

This review presents the evidence from old and recent trials relevant to optimal blood pressure levels in diabetes mellitus, aiming to shed light in this major clinical question [read more].
Papadopoulou E et al. J Hum Hypertens 2018. doi: 10.1038/s41371-018-0079-5

Get more on:  Diabetic complications | Type 2 diabetes

Journal article

Relationship between sleep disturbance and self-care in adults with type 2 diabetes

Man struggling to sleep (symbolic image with model)

The authors examined the relationship between sleep disturbance and self-care in adults with type 2 diabetes, including both subjective and objective sleep assessments and controlling for potential covariates [read more].
Zhu B et al. Acta Diabetol 2018. doi: 10.1007/s00592-018-1181-4

Get more on:  Diabetic complicationsType 2 diabetes

Journal article

Association between dietary protein intake and type 2 diabetes varies by dietary pattern

High-protein food

The authors examine the association between protein intake and type 2 diabetes mellitus in different dietary patterns [read more].
Ke Q et al. Diabetol Metab Syndr 2018; 10: 48. doi: 10.1186/s13098-018-0350-5

Get more on:  Lifestyle interventions | Prediabetes and prevention |  Type 2 diabetes

Journal article

Pioglitazone use and risk of bladder cancer: A systematic literature review and meta-analysis of observational studies

Bladder cancer (illustration)

This meta-analysis of observational studies assesses the association between risk of bladder cancer and exposure to pioglitazone among subjects with type 2 diabetes [read more].
Mehtälä J et al. Diabetol Int 2018. doi: 10.1007/s13340-018-0360-4

Get more on:  Diabetic complications | Medication | Type 2 diabetes

Journal article

A randomized controlled trial of dapagliflozin plus once-weekly exenatide versus placebo in individuals with obesity and without diabetes: Metabolic effects and markers associated with bodyweight loss

Woman measuring her waist (symbolic image with model)

This post hoc analysis investigated the metabolic effects and baseline associations with bodyweight loss on coadministration of dapagliflozin and exenatide once weekly among adults with obesity and without diabetes [read more].
Pereira MJ et al. Diabetes Ther 2018. doi: 10.1007/s13300-018-0449-6

Get more on:  Medication | Obesity | Type 2 diabetes

Journal article

Long-term effect of the color record method in self-monitoring of blood glucose on metabolic parameters in type 2 diabetes: A 2-year follow-up of the Color IMPACT study

Paper ECG

This article evaluates the potential long-term effect of two different color indication methods for self-monitoring of blood glucose on metabolic parameters in insulin-treated type 2 diabetes [read more].
Nishimura A et al. Diabetes Ther 2018. doi: 10.1007/s13300-018-0457-6

Get more on:  Devices and technology | Type 2 diabetes

medwireNews editor’s pick

First trimester metformin exposure unlikely to raise congenital anomaly risk

Pregnancy

A European-wide case–control study finds little evidence for risk to the developing fetus if a mother is taking metformin.

medwireNews editor's pick

NPH insulin may be as good as analogs in type 2 diabetes

Insulin pens

Patients with type 2 diabetes in clinical practice have similar outcomes regardless of whether they use long-acting insulin analogs or the cheaper human neutral protamine Hagedorn insulin, say researchers.

Practice tip: View from the clinic

Best communication practices for subspecialty referrals

Best communication practices for subspecialty referrals

Jay Shubrook draws on his experiences as a primary care physician and diabetes specialist to provide simple tips to help each profession optimize the patient referral process [read more].

Get more on: Healthcare systems and type 1 diabetes | Healthcare systems and type 2 diabetes | View from the clinic

Journal article

Chronic kidney disease-induced insulin resistance: Current state of the field

Kidneys and urinary bladder (illustration)

This review will evaluate mechanisms responsible for chronic kidney disease-induced insulin resistance and therapies currently available [read more].
Dave N, Wu J, Thomas S. Curr Diab Rep 2018; 18: 44. doi: 10.1007/s11892-018-1010-8

Get more on:  Diabetic complications | Type 1 diabetes | Type 2 diabetes

Journal article

Prevalence of cardiovascular disease in type 2 diabetes: A systematic literature review of scientific evidence from across the world in 2007–2017

Stethoscope and globe

The aim of this study was to estimate the current prevalence of cardiovascular disease among adults with type 2 diabetes by reviewing recently published existing literature [read more].
Einarson TR et al. Cardiovasc Diabetol 2018; 17: 83. doi: 10.1186/s12933-018-0728-6

Get more on: Diabetic complications | Type 2 diabetes

medwireNews@ADA2018

OBSERVE-4D: Canagliflozin amputation risk not replicated in real-world data

New Content Item

A study of patients from US administrative claims databases finds no evidence that use of canagliflozin increases the risk for below the knee amputation when compared with other sodium-glucose cotransporter 2 inhibitors or with other antidiabetic medications.

medwireNews@ADA2018

Significant metabolic benefits seen with dual receptor agonist MEDI0382

Syringe_vials

MEDI0382, a novel glucagon-like peptide-1 and glucagon receptor dual agonist, induces clinically meaningful improvements in glycemic control and bodyweight in patients with type 2 diabetes, show data published in The Lancet.

medwireNews@ADA2018

RISE: Early insulin does not slow beta cell decline in youth with type 2 diabetes

Islet cells

The RISE trial investigators have found that increased insulin resistance and hyperresponsive beta cells may explain the rapid progression of type 2 diabetes in children.

medwireNews@ADA2018

Closed-loop delivery improves inpatient glucose control in type 2 diabetes

Hospital

Fully closed-loop insulin delivery results in a markedly improved time in range among inpatients with type 2 diabetes receiving noncritical care, researchers have reported.

medwireNews@ADA2018

VADT: Legacy effect fizzles out over time

New Content Item

The 15-year results of the VADT reveal that the legacy cardioprotective effect of intensive glycemic control seen at the 10-year follow-up has now disappeared.

medwireNews editor's pick

Single blood sample could be sufficient for diabetes diagnosis

Blood sample

Researchers studying the ARIC cohort have found that virtually all people with elevated fasting plasma glucose and glycated hemoglobin in the same blood sample went on to develop diabetes.

Practice tips: Podcast

Barriers to insulin: Initiation in type 2 diabetes patients

Lori Podcast 1

Editorial Board member Lori Berard talks through the stages and challenges associated with preparing type 2 diabetes patients for insulin therapy [listen to the podcast 9:00].

Get more on: Type 2 diabetes | Insulin | Hypoglycemia

Expert opinion: Editorial

Hit early, hit hard: The EADSG insulin guidelines

Stethoscope and map

Sanjay Kalra and Silver Bahendeka, East Africa Diabetes Study Group Chair, provide an overview of the latest insulin guidance developed to aid management in a challenging region, facing familiar struggles [read more].

Get more on: Medications | Type 1 diabetes | Type 2 diabetes

Journal article

Successful management of poorly controlled type 2 diabetes with multidisciplinary neurobehavioral rehabilitation: A case report and review

Smiling doctors

We present one successful case that demonstrates a significantly beneficial effect of physical exercise and lifestyle intervention in the management of type 2 diabetes mellitus [read more].
Deng Z et al. Diabetes Ther 2018. doi: 10.1007/s13300-018-0448-7

Get more on: Type 2 diabetes | Physical activity | Lifestyle interventions​​​​​​​

04-17-2018 | Dipeptidyl peptidase-4 inhibitors | At a glance | Article

Round up of the DPP-4 inhibitor CV outcome trials

medwireNews provides a brief overview of the published and ongoing dipeptidyl peptidase-4 inhibitorscardiovascular outcomes trials.

09-19-2017 | Hypertension | Practical approach | Article

A practical approach to hypertension management in diabetes

Hypertension is an important comorbidity of diabetes, contributing significantly to death and disability. This article provides a practical approach to managing hypertension in patients with diabetes.

10-17-2017 | Glucagon-like peptide-1 agonists | At a glance | Article

Round up of the GLP-1 receptor agonist CV outcome trials

medwireNews provides a brief overview of the published and ongoing glucagon-like peptide-1 receptor agonist cardiovascular outcomes trials.

Downloadable slides

12-21-2017 | Collection

FreeStyle Libre collection

These slide sets summarize the results of randomized controlled trials investigating the use of flash glucose-sensing technology in patients with diabetes.

Funded by an educational grant from Abbott Diabetes Care

Themed collections

06-25-2018 | Sodium-glucose cotransporter-2 inhibitors | Themed collection | Collection

Sodium-glucose cotransporter-2 inhibitors in type 2 diabetes

An updated collection of articles focusing on the mechanism of action and clinical use of sodium-glucose cotransporter-2 inhibitors in patients with diabetes.

Journal articles and book chapters

Guidelines

A convenient single access point, providing diabetes professionals with links to a comprehensive set of clinical practice guidelines from a wide range of relevant organizations.

Slides

Downloadable PowerPoint slide sets containing a variety of high-quality images and illustrations from Springer Nature’s library of published figures.

Practice tips

Practical information, guidance, and helpful resources for diabetes healthcare providers. Comprised of practical approaches, case studies, and more.

Themed collections

Compendia of selected, recently published, free full-text journal and book content from Springer Nature and other publishers on a particular topic within diabetes management, as recommended by our Editorial Board.

Independent Medical Education

Educational programs building upon the most current research and professional practice recommendations, with the aim of enabling more efficient diagnosis, optimizing treatment, and improving patient outcomes.

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