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Obesity

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Support for bariatric surgery in people with insulin-dependent type 2 diabetes

Gastric bypass surgery (used with permission)

Treatment with bariatric surgery is associated with clinical and cost-saving benefits among obese people with type 2 diabetes requiring insulin, researchers report.

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Metformin might protect women with type 2 diabetes against COVID-19 mortality

Female in mask holding pill

An observational study suggests that prior metformin use may offer a protective effect against COVID-19 mortality in people with type 2 diabetes, but only for women.

EASD 2020 news

Intermittent very-low-calorie diet could be easier to stomach for people with diabetes

Man checking body fat (symbolic image with model)

The pilot MIDDAS study suggests that a 2-day per week very-low-calorie diet could be a viable alternative to a continuous diet for people with type 2 diabetes who struggle with this approach.

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‘Nearly identical’ metabolic benefits with surgery vs diet in people with type 2 diabetes

Bariatric surgery

Among people with obesity and type 2 diabetes, substantial weight loss is associated with similar metabolic benefits irrespective of whether it is achieved through gastric bypass surgery or diet, suggests research published in The New England Journal of Medicine.

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Type 1, type 2 diabetes linked to elevated COVID-19 mortality risk

Doctor checking on Covid-19 infected patient connected to a ventilator

Both type 1 and type 2 diabetes are independently associated with an increased risk for death among hospitalized patients with COVID-19, and a number of factors including poor glycemic control and BMI may predict mortality risk, suggest findings from two studies published in The Lancet Diabetes & Endocrinology.

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Ethnic-specific diabetes screening BMI cutoffs proposed

African American male patient having weight checked by doctor

Researchers studying the MESA cohort have proposed BMI cutoffs at which people from ethnic minorities should be screened for type 2 diabetes, all of which are lower than their proposed cutoff for White people.

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Cardiometabolic burden varies by age, sex, ethnicity at type 2 diabetes diagnosis

People in profile different age and nationalities

A study shows marked variations in cardiovascular risk burden according to age, sex, and ethnicity at the point of type 2 diabetes diagnosis, with implications for both diabetes prevention and cardiovascular risk management.

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Exercise better than diet to combat early heart changes in type 2 diabetes

Older couple exercising in the park

The results of a small randomized trial suggest exercise is more helpful than diet for combating early cardiac dysfunction associated with type 2 diabetes, although both may be beneficial.

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Liraglutide 3.0 mg boosts weight loss in insulin-dependent type 2 diabetes

Insulin pens

Adding liraglutide 3.0 mg to intensive behavioral therapy increases weight loss in overweight or obese people with insulin-treated type 2 diabetes, results of the phase 3 SCALE Insulin trial show.

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Preoperative diabetes duration may affect remission rates after bariatric surgery

Bariatric surgery

Swedish research suggests that determining type 2 diabetes duration prior to bariatric surgery could help prioritize those patients most likely to achieve diabetes remission.

01-12-2021 | Diet | News

Ghrelin changes predict weight regain after DiRECT diet

Ghrelin is the only appetite-related hormone that predicted weight regain among the participants of the DiRECT trial, say the researchers.

01-12-2021 | Adolescents | News

Obesity flags high-risk cardiorenal profile in youth with type 1 diabetes

Adolescents with type 1 diabetes who are obese have a cardiorenal risk profile similar to that of their peers with type 2 diabetes, say researchers.

01-08-2021 | Non-alcoholic fatty liver disease | News

Liver fibrosis common in type 2 diabetes

Researchers have detected moderate or severe liver fibrosis in around one in six people with type 2 diabetes.

12-14-2020 | Metabolic surgery | News

Support for bariatric surgery in people with insulin-dependent type 2 diabetes

Treatment with bariatric surgery is associated with clinical and cost-saving benefits among obese people with type 2 diabetes requiring insulin, researchers report.

12-09-2020 | Liraglutide (obesity) | News

Liraglutide gets FDA go-ahead for teens with obesity

Click through to read more on this announcement

12-08-2020 | COVID-19 | News

Metformin might protect women with type 2 diabetes against COVID-19 mortality

An observational study suggests that prior metformin use may offer a protective effect against COVID-19 mortality in people with type 2 diabetes, but only for women.

12-03-2020 | Epidemiology | News

‘Remarkably high’ lifetime risk for developing diabetes in metropolitan cities in India

People living in metropolitan cities in India have a high likelihood of developing diabetes, with a particularly elevated risk in overweight and obese individuals, research shows.

11-27-2020 | Cardiovascular disorders | News

Healthy lifestyle mitigates elevated heart disease risk in people with type 2 diabetes

People with type 2 diabetes have around a fourfold increased risk for heart disease relative to those without, but having a healthy lifestyle may lessen this risk, researchers report.

11-19-2020 | Heart failure | News

Targeting fat mass, central adiposity may reduce HF risk in type 2 diabetes

The risk for heart failure falls significantly with reductions in fat mass and waist circumference in overweight or obese people with type 2 diabetes, shows an analysis of data from the Look AHEAD trial.

10-21-2020 | COVID-19 | News

Obesity may be less impactful for older COVID-19 patients with type 2 diabetes

Obesity is a significant predictor of poor COVID-19 outcomes in patients who also have type 2 diabetes, but only in those up to the age of 75 years, report French researchers.

10-14-2020 | Tirzepatide | At a glance | Article

A quick guide to the SURPASS and SURMOUNT trials

Tirzepatide (formerly known as LY3298176) is a novel glucose-lowering medication that stimulates the receptors for both glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1.

10-13-2020 | Metabolic surgery | News

Bariatric surgery cuts pancreatic cancer risk in obese individuals with diabetes

Bariatric surgery is associated with a reduced prevalence of pancreatic cancer in obese individuals with type 2 diabetes, suggest findings from a population-based study presented at UEG Week Virtual 2020.

10-09-2020 | Diet | News

Pancreatic morphology normalizes with sustained type 2 diabetes remission

Sustained remission of type 2 diabetes in DiRECT was accompanied by normalization of pancreatic morphology, say the researchers.

09-25-2020 | EASD 2020 | Conference coverage | News

Ethnicity, obesity linked to risk for early-onset type 2 diabetes

The development of type 2 diabetes at a young age disproportionately affects people of South Asian and African–Caribbean ethnicity, and obesity is associated with early-onset diabetes in all ethnic groups, indicates research presented at the virtual 56th EASD Annual Meeting.

DiRECT: Type 2 diabetes remission through weight management

Primary findings, 2-year outcomes and translating this landmark trial into practice

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