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UKPDS 

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  1. 09-30-2018 | UKPDS | Feature | Article

    The UKPDS: A lasting legacy

    Twenty years after the publication of the primary findings, medwireNews talks to longtime UKPDS investigator Professor David Matthews (University of Oxford, UK) about the struggles of the team to bring the trial to completion and the impact of the findings on diabetes care.

  2. 09-30-2018 | UKPDS | At a glance | Article

    What we learned from the UKPDS

    The UKPDS has so far generated an astonishing 93 original research papers.  medwireNews ​​​​​​​ rounds them up.

  3. 10-27-2004 | Type 2 diabetes | Article

    A model to estimate the lifetime health outcomes of patients with type 2 diabetes: The United Kingdom Prospective Diabetes Study (UKPDS) Outcomes Model

    Clarke PM et al. Diabetologia 2004; 47: 1747–1759. doi: 10.1007/s00125-004-1527-z

  4. 06-22-2013 | Epidemiology | Article

    UKPDS Outcomes Model 2: A new version of a model to simulate lifetime health outcomes of patients with type 2 diabetes mellitus using data from the 30 year United Kingdom Prospective Diabetes Study

    Hayes AJ et al. Diabetologia 2013; 56: 1925–1933. doi: 10.1007/s00125-013-2940-y

  5. 10-01-1993 | Hypertension | Article

    UK Prospective Diabetes Study (UKPDS). X. Urinary albumin excretion over 3 years in diet-treated type 2, (non-insulin-dependent) diabetic patients, and association with hypertension, hyperglycemia and hypertriglyceridemia

    Cull CA et al. Diabetologia 1993; 36: 1021–1029. doi: 10.1007/BF02374494

  6. 09-01-1993 | Hypertension | Article

    UK Prospective Diabetes Study (UKPDS). IX: Relationships of urinary albumin and N-acetylglucosaminidase to glycemia and hypertension at diagnosis of type 2 (non-insulin-dependent) diabetes mellitus and after 3 months diet therapy

    UKPDS Study Group.  Diabetologia  1993; 36: 835–842. doi: 10.1007/BF00400359

  7. 09-01-1999 | Genetics | Article

    Sequence variants of the sarco(endo)plasmic reticulum Ca2+-transport ATPase 3 gene (SERCA3) in Caucasian type 2 diabetic patients (UKPDS 48)

    Varadi A et al. Diabetologia 1999; 42: 1240–1243. doi: 10.1007/s001250051298

  8. 08-01-1995 | Cardiovascular disorders | Article

    UK prospective diabetes study (UKPDS) 14: Association of angiotensin-converting enzyme insertion/deletion polymorphism with myocardial infarction in NIDDM

    Keavney BD et al. Diabetologia 1995; 38: 948–952. doi: 10.1007/BF00400584

  9. 02-01-2001 | Retinopathy | Article

    UKPDS 50: Risk factors for incidence and progression of retinopathy in type 2 diabetes over 6 years from diagnosis

    Stratton IM et al. Diabetologia 2001; 44: 1546–1563. doi: 10.1007/s001250051594

  10. 11-01-1996 | Genetics | Article

    UKPDS 19: Heterogeneity in NIDDM: Separate contributions of IRS-1 and b3-adrenergic-receptor mutations to insulin resistance and obesity respectively with no evidence for glycogen synthase gene mutations

    Zhang Y et al. Diabetologia 1996; 39: 1505–1511. doi: 10.1007/s001250050605

  11. 03-01-2001 | Metformin | Article

    Cost-effectiveness analysis of intensive blood-glucose control with metformin in overweight patients with type 2 diabetes (UKPDS No. 51)

    Clarke P et al. Diabetologia 2001; 44: 298–304. doi: 10.1007/s001250051617

  12. 08-01-1999 | Retinopathy | Article

    Microaneurysms in the development of diabetic retinopathy (UKPDS 42)

    Kohner EM et al. Diabetologia 1999; 42: 1107–1112. doi: 10.1007/s001250051278

  13. 04-01-1999 | Genetics | Article

    Genetic heterogeneity of autoimmune diabetes: Age of presentation in adults is influenced by HLA DRB1 and DQB1 genotypes (UKPDS 43)

    Horton VA et al. Diabetologia 1999; 42: 608–616. doi: 10.1007/s001250051202

  14. 02-24-2005 | Pathophysiology | Article

    Islet autoantibodies in clinically diagnosed type 2 diabetes: Prevalence and relationship with metabolic control (UKPDS 70)

    Davis TME et al. Diabetologia 2005; 48: 695–702. doi: 10.1007/s00125-005-1690-x

  15. 03-12-2005 | Pathophysiology | Article

    IA-2 antibody prevalence and risk assessment of early insulin requirement in subjects presenting with type 2 diabetes (UKPDS 71)

    Bottazzo GF et al. Diabetologia 2005; 48: 703–708. doi: 10.1007/s00125-005-1691-9

  16. 04-15-2005 | Hypertension | Article

    Cost-utility analyses of intensive blood glucose and tight blood pressure control in type 2 diabetes (UKPDS 72)

    Clarke PM et al. Diabetologia 2005; 48: 868–877. doi: 10.1007/s00125-005-1717-3

  17. 05-31-2006 | Hypertension | Article

    Additive effects of glycaemia and blood pressure exposure on risk of complications in type 2 diabetes: A prospective observational study (UKPDS 75)

    Stratton IM et al. Diabetologia 2006; 49: 1761–1769. doi: 10.1007/s00125-006-0297-1

  18. 10-03-2006 | Nephropathy | Article

    Paraoxonase 2 (PON2) polymorphisms and development of renal dysfunction in type 2 diabetes: UKPDS 76

    Calle R et al. Diabetologia 2006; 49: 2892–2899. doi: 10.1007/s00125-006-0436-8

  19. 07-07-2023 | Type 2 diabetes | News | Article

    New atherothrombotic risk score for type 2 diabetes

    The researchers say the discrimination of their risk score compares “favorably” with existing risk scores such as the SMART Risk score, the UKPDS Cardiovascular Risk Engine, and the ADVANCE-Risk Score.

  20. 07-26-2021 | Glycemic control | News | Article

    Delayed impact of high glucose levels may explain legacy effect

    The so-called legacy effect of a period of good glycemic control in type 2 diabetes may be because the greatest impact of hyperglycemia occurs many years in the future, show data from the UKPDS.

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