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Type 2 diabetes and hypoglycemia

medwireNews editor's pick

Hepatic glucokinase activation may improve glycemic control in type 2 diabetes

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The hepatoselective glucokinase activator TTP399 reduces glycated hemoglobin levels without increasing the risk for hypoglycemia among patients with type 2 diabetes, suggest findings from the phase IIb AGATA trial.

Interactive patient case study

Hypoglycemia and technology

Hypoglycemia and technology

This 15-minute case presents the identification of problematic hypoglycemia and the appropriate use and monitoring of different technologies in the context of reducing the occurrence and risk of hypoglycemia.

Get more on: Hypoglycemia | Devices and technology | Pediatric diabetes

Case study

Acute illness while on a SGLT2 inhibitor and ketogenic diet

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Advisory Board member Theresa Smyth tackles an emergency case involving a type 2 diabetes patient on a new diet and treated with empagliflozin. What went wrong and how should he be managed? [Read more].

Get more on: SGLT2 inhibitors | Diet and nutritional management

medwireNews editor's pick

Continuing metformin advisable for patients starting sulfonylurea treatment

Metformin formula

Research shows that starting second-line sulfonylurea treatment is associated with an increased risk for cardiovascular and hypoglycemic events among patients with type 2 diabetes in clinical practice, although the risk is less if they continue using metformin rather than switching completely.

Journal article

Long-term effect of the color record method in self-monitoring of blood glucose on metabolic parameters in type 2 diabetes: A 2-year follow-up of the Color IMPACT study

Paper ECG

This article evaluates the potential long-term effect of two different color indication methods for self-monitoring of blood glucose on metabolic parameters in insulin-treated type 2 diabetes [read more].
Nishimura A et al. Diabetes Ther 2018. doi: 10.1007/s13300-018-0457-6

Get more on:  Devices and technology | Type 2 diabetes

medwireNews editor's pick

NPH insulin may be as good as analogs in type 2 diabetes

Insulin pens

Patients with type 2 diabetes in clinical practice have similar outcomes regardless of whether they use long-acting insulin analogs or the cheaper human neutral protamine Hagedorn insulin, say researchers.

Expert opinion interview

Barriers to insulin: Initiation in type 2 diabetes patients

Lori Podcast 1

Editorial Board member Lori Berard talks through the stages and challenges associated with preparing type 2 diabetes patients for insulin therapy [listen to the interview 9:00].

Get more on: Type 2 diabetes | Insulin | Hypoglycemia

Expert opinion editorial

Hit early, hit hard: The EADSG insulin guidelines

Stethoscope and map

Sanjay Kalra and Silver Bahendeka, East Africa Diabetes Study Group Chair, provide an overview of the latest insulin guidance developed to aid management in a challenging region, facing familiar struggles [read more].

Get more on: Medications | Type 1 diabetes | Type 2 diabetes

Journal article

Glycemic impact of non-nutritive sweeteners: A systematic review and meta-analysis of randomized controlled trials

Person holding sweeteners

A systematic review and meta-analysis of randomized controlled trials was conducted to quantitatively synthesize existing scientific evidence on the glycemic impact of non-nutritive sweeteners [read more].
Nichol AD, Holle MJ, An R. Eur J Clin Nutr 2018. doi: 10.1038/s41430-018-0170-6

Get more on: Type 2 diabetes | Glycemic control | Diet and nutritional management

medwireNews editor's pick

Support for alogliptin as add-on therapy for type 2 diabetes

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Adding the dipeptidyl peptidase-4 inhibitor alogliptin to metformin and sulfonylurea treatment may improve glycemic control in patients with type 2 diabetes and high cardiovascular risk, a post-hoc analysis of the EXAMINE trial suggests.

medwireNews

01-17-2019 | Glucokinase activators | Highlight | News

Hepatic glucokinase activation may improve glycemic control in type 2 diabetes

The hepatoselective glucokinase activator TTP399 reduces glycated hemoglobin levels without increasing the risk for hypoglycemia among patients with type 2 diabetes, suggest findings from the phase IIb AGATA trial.

07-18-2018 | Sulfonylureas | Highlight | News

Continuing metformin advisable for patients starting sulfonylurea treatment

Research shows that starting second-line sulfonylurea treatment is associated with an increased risk for cardiovascular and hypoglycemic events among patients with type 2 diabetes in clinical practice, although the risk is less if they continue using metformin rather than switching completely.

07-09-2018 | Insulin | News

Few efficacy and safety differences between long-acting insulins

The results of a network meta-analysis suggest that long-acting insulin analogs have broadly equivalent efficacy and safety in patients with type 2 diabetes, although some might be a little better for preventing nocturnal hypoglycemia.

Downloadable slides

10-31-2018 | Slideset | Collection

FreeStyle Libre collection

These slide sets summarize the results of randomized controlled trials investigating the use of flash glucose-sensing technology in patients with diabetes.

Funded by an educational grant from Abbott Diabetes Care

Themed collections

06-25-2018 | SGLT2 inhibitors | Themed collection | Collection

Sodium-glucose cotransporter-2 inhibitors in type 2 diabetes

An updated collection of articles focusing on the mechanism of action and clinical use of sodium-glucose cotransporter-2 inhibitors in patients with diabetes.

Journal articles and book chapters

08-15-2018 | Pregnancy | Review | Article

Inpatient glycemic management of the pregnant patient

Yeh T, Yeung M, Mendelsohn Curanaj FA. Curr Diab Rep 2018; 18: 73. doi: 10.1007/s11892-018-1045-x

07-23-2018 | SGLT2 inhibitors | Review | Article

SGLT2 inhibitors in type 2 diabetes management: Key evidence and implications for clinical practice

Wilding J et al. Diabetes Ther 2018. doi: 10.1007/s13300-018-0471-8

Guidelines

A convenient single access point, providing diabetes professionals with links to a comprehensive set of clinical practice guidelines from a wide range of relevant organizations.

Slides

Downloadable PowerPoint slide sets containing a variety of high-quality images and illustrations from Springer Nature’s library of published figures.

Practice tips

Practical information, guidance, and helpful resources for diabetes healthcare providers. Comprised of practical approaches, case studies, and more.

Themed collections

Compendia of selected, recently published, free full-text journal and book content from Springer Nature and other publishers on a particular topic within diabetes management, as recommended by our Editorial Board.

Independent Medical Education

Educational programs building upon the most current research and professional practice recommendations, with the aim of enabling more efficient diagnosis, optimizing treatment, and improving patient outcomes.

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