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GLP-1 receptor agonists


Browse the latest news, expert commentary, and educational content on the GLP-1 receptor agonist medication class.


Initiating GLP-1 receptor agonists: Managing side effects

Specialist nurse Nicola Milne discusses the side effects that can arise in people with type 2 diabetes during initiation of GLP-1 receptor agonists, and how to best manage them.

The STEP and SELECT trials

The STEP and SELECT trials

Keep up with the news and expert comment on the STEP and SURMOUNT phase 3 trials of semaglutide 2.4 mg in people with obesity.

The SURPASS trials

The SURPASS trials

Click through for clinical trial updates and expert reaction to the SURPASS and SURMOUNT phase 3 trials of the novel dual-action medication tirzepatide in people with type 2 diabetes and/or obesity.

Beyond glucose lowering | Cardioprotection

10-17-2017 | GLP-1 agonists | At a glance | Article

Round up of the GLP-1 receptor agonist CV outcome trials

medwireNews provides a brief overview of the published and ongoing glucagon-like peptide-1 receptor agonist cardiovascular outcomes trials.

07-02-2019 | Dulaglutide | Podcast | Article

REWIND, DECLARE, and high-risk diabetes patients

How will the findings of the REWIND trial and the DECLARE-TIMI 58 renal outcomes analysis affect treatment decisions for high-risk diabetes patients without overt cardiovascular disease? medwireNews asks Kamlesh Khunti.

01-30-2019 | Cardiovascular outcomes | Case study | Article

Cardiovascular risk reduction in type 2 diabetes

Pharmacological management of comorbid cardiovascular risk and type 2 diabetes is undergoing a paradigm shift. General practitioner Kevin Fernando puts recommendations from the ADA/EASD into practice in this patient case study.

Beyond glucose lowering | Novel formulations

Neil Skolnik

04-29-2020 | Type 2 diabetes | Podcast | Article

Is oral semaglutide a game changer or nice-to-have for type 2 diabetes?

US primary care physician Neil Skolnik discusses the role of oral semaglutide in the care of people with type 2 diabetes and outlines key considerations for its use (12:26).

Balancing pros and cons

05-06-2020 | Type 2 diabetes | Editorial | Article

Oral semaglutide: A technical triumph, with caveats

Diabetologist and Editorial Board member John Wilding gives his opinion on the latest addition to the GLP-1RA class, oral semaglutide.

The clinical trials

10-14-2020 | Tirzepatide | At a glance | Article

A quick guide to the SURPASS and SURMOUNT trials

Phase 3 and 4 trials of tirzepatide in type 2 diabetes and obesity

Read our overview of the SURPASS trials of the dual GLP-1/GIP receptor agonist tirzepatide in people with type 2 diabetes, plus the SURMOUNT trials in people with obesity.

02-11-2021 | Semaglutide | At a glance | Article

A quick guide to the STEP trials

Read our round-up of the STEP phase 3 trials of semaglutide 2.4 mg in people with obesity, plus the SELECT cardiovascular outcomes trial.

07-03-2019 | Semaglutide | At a glance | Article

A quick guide to the PIONEER trials

medwireNews rounds up the ongoing, reported, and published trials from the PIONEER oral semaglutide program.

04-07-2017 | Semaglutide | At a glance | Article

A quick guide to the SUSTAIN trials

02-07-2022 | Dulaglutide | At a glance | Article

A quick guide to the AWARD trials

08-09-2022 | Lixisenatide | At a glance | Article

A quick guide to the GetGoal trials

08-09-2022 | Liraglutide (T2DM) | At a glance | Article

A quick guide to the LEAD trials

02-08-2022 | Exenatide | At a glance | Article

A quick guide to the DURATION trials