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Diabetic complications

Diabetic complications

03-25-2019 | Hypoglycemia | News

Problem of hypoglycemia unawareness highlighted in older people with type 1 diabetes

Baseline data from the WISDM trial show that older adults with type 1 diabetes who have impaired awareness of hypoglycemia symptoms can spend over half an hour per day with extremely low blood glucose levels.

Diabetes and dementia: Addressing the needs of an overlooked population

03-04-2019 | Mental health | Editorial | Article

Diabetes and dementia: Addressing the needs of an overlooked population

Diabetologist Amar Puttanna addresses growing concerns about the rise of dementia in diabetes care and highlights where guidelines, research efforts, and management options are needed to tackle this comorbidity.

12-19-2018 | Older adults | News

Type 2 diabetes may hasten cognitive decline

A prospective study reveals accelerated declines in some measures of cognitive performance among people with type 2 diabetes.

08-14-2018 | Depression | News

Depressive symptoms forecast disability in older adults with recent diabetes

An increase in depressive symptoms around the time of a new diabetes diagnosis in older adults is associated with increasing difficulty in performing daily activities such as shopping, walking, and dressing, US researchers report.

08-02-2018 | Depression | Article

Trajectory of disability in older adults with newly diagnosed diabetes: Role of elevated depressive symptoms

Wu CY et al. Diabetes Care 2018: dc180007. doi: 10.2337/dc18-0007

07-18-2018 | Mental health | Review | Article

Cognitive decline and dementia in diabetes mellitus: Mechanisms and clinical implications

Biessels GJ, Despa F. Nat Rev Endocrinol 2018. doi: 10.1038/s41574-018-0048-7

07-06-2018 | Osteoporosis | Article

FRAX tool in type 2 diabetic subjects: The use of HbA1c in estimating fracture risk

Valentini A et al. Acta Diabetol 2018. doi: 10.1007/s00592-018-1187-y

07-04-2018 | Mental health | Article

Factors associated with type 2 diabetes in patients with vascular dementia: A population-based cross-sectional study

Liu CL et al. BMC Endocr Disord 2018; 18: 45. doi: 10.1186/s12902-018-0273-z

06-24-2018 | Insulin degludec | ADA 2018 | News

Degludec benefits consistent in elderly patients

Degludec delivers the same magnitude of protection against hypoglycemia relative to glargine across patient age groups, shows analysis of the SWITCH 2 and DEVOTE trials.

06-21-2018 | Sleep disorders | Article

Relationship between sleep disturbance and self-care in adults with type 2 diabetes

Zhu B et al. Acta Diabetol 2018. doi: 10.1007/s00592-018-1181-4

06-06-2018 | Mental health | Article

The relationship between sleep and cognitive function in patients with prediabetes and type 2 diabetes

Saetung S et al. Acta Diabetol 2018. doi: 10.1007/s00592-018-1166-3

Elderly patient with doctor

06-06-2018 | Type 1 diabetes | Case report | Article

Sudden onset of immune-mediated type 1 diabetes mellitus in a 93-year-old woman: A case report

Oriot P et al. Acta Diabetol 2018. doi: 10.1007/s00592-018-1170-7

05-25-2018 | Diabetes self-management | Article

Type 1 diabetes self-management from emerging adulthood through older adulthood

McCarthy MM, Grey M. Diabetes Care 2018. doi: 10.2337/dc17-2597

Elderly diabetic patient (symbolic image with models)

04-19-2018 | Older adults | Highlight | News

Glycemic variability modifies mortality risk in older diabetes patients

The excess mortality risk associated with high or very low glycated hemoglobin values is modified by glycemic variability in diabetes patients aged 70 years or more, shows an analysis of The Health Improvement Network database.

Elderly diabetic patient (symbolic image with models)

02-19-2018 | Older adults | Practical approach | Article

Diabetes in the elderly

This review takes a practical approach to the assessment, nursing care, and medical treatment of diabetes in the elderly, highlighting major challenges and suggesting solutions to common clinical problems.

Pill in hand (symbolic image with model)

02-13-2018 | Older adults | Editorial | Article

Does setting treatment targets risk the overtreatment of type 2 diabetes in older patients?

The drive to achieve lower HbA1c targets in older patients is not without concern or risk. Our UK Board address concerns highlighted by recent trials and discuss whether current guidelines do enough to mitigate the risks of overtreatment.

Editorial Board member Jay Shubrook follows up with treatment individualization specialist David Strain on the treatment challenges presented by older adults, and the implications for tailoring hypertension therapy in this diverse population (11:08).



Learning points include:

  • The rationale for emphasizing quality over quantity of life in certain subsets of the elderly patient population.
  • The importance of incorporating understanding of key comorbidities into treatment planning, including:
    • Left ventricular and/or diastolic dysfunction
    • Chronic kidney disease 
    • Benign prostatic hyperplasia
    • Heart failure
  • Single/multi-agent therapies capable of targeting hypertension and its comorbidities.
  • The importance of early renal function testing in older adults initiated on treatments for hypertension and its comorbidities.
  • Understanding renal impairment risks in vulnerable adults treated with angiotensin-converting-enzyme (ACE) inhibitors in patients.
  • Understanding the relative risk of hyponatremia with generally well-tolerated treatments like as thiazide diuretics.
  • Best practice for avoiding adverse drug events in the acute setting.
  • The challenges associated with treating concomitant heart failure in older adults.

« Video 4: Individualization of diabetes treatment: Considerations for frail, elderly patients with heart failure

Human brain

01-26-2018 | Complications | News

Diabetes, poor glycemic control associated with long-term cognitive decline

Results of a longitudinal study show that diabetes and poor glycemic control are associated with long-term cognitive decline among older people in the UK.

12-22-2017 | Depression | News

Depression and severe dysglycemia increase the risk for each other

A bidirectional relationship between depression and severe dysglycemia exists among older people with type 1 diabetes, indicating a need for increased vigilance in this population.