Monogenic diabetes

Yeung RO et al. Rev Endocr Metab Disord 2018. doi: 10.1007/s11154-018-9446-3

Dickens LT, Naylor RN. Curr Diab Rep 2018; 18: 12. doi: 10.1007/s11892-018-0982-8

The second case study in our series on atypical forms of diabetes from Jay Shubrook presents a highly distinct variation of the disease and challenges you to make the correct diagnosis.

Genet Med 2017. doi: 10.1038/gim.2017.150

Romano F et al. Acta Diabetol 2017; 54: 1139. doi: 10.1007/s00592-017-1057-z

Studies presented in a session on the genetics of diabetes, at the EASD annual meeting in Lisbon, Portugal, demonstrated the heterogeneity of type 1 diabetes risk and the predictive and diagnostic power of a genetic risk score.

Neonatal diabetes could be detected as early as day 5 of life using glucose measurements from dried blood spots, researchers report.

McDonald TJ et al. Diabetologia 2017; 60: 2168–2173. doi: 10.1007/s00125-017-4383-3

Researchers have developed a new biomarker screening pathway to systematically screen all patients with young-onset diabetes for monogenic diabetes.

Researchers report two cases of children with severe and irreversible neurologic damage caused by complications at the time of neonatal diabetes diagnosis, highlighting the need for increased awareness of the condition.

Owen KR. In: Endocrinology and Diabetes. Edited by Ajjan R, Orme S. Springer, London, 2015. doi: 10.1007/978-1-4471-2789-5_20

Genetic analysis of children in a national registry reveals undiagnosed maturity-onset diabetes of the young among antibody-negative patients with type 1 diabetes, with implications for their treatment.

Arce, KM, Pantalone KM. Diabetes Ther 2016; 7: 369. doi: 10.1007/s13300-016-0171-1

UKPDS Study Group. Diabetologia 1983; 24: 404–411. doi: 10.1007/BF00257337