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04-26-2016 | Neonatal diabetes | Case report | Article

Not All Diabetes in Infants is Type 1: A Case Report

Diabetes Therapy

Authors: Karla M. Arce, Kevin M. Pantalone

Publisher: Springer Healthcare


Neonatal diabetes mellitus (NDM), defined as persistent hyperglycemia occurring in the first months of life, is a rare cause of hyperglycemia and is often misdiagnosed as type 1 diabetes mellitus (T1DM). Numerous reports have shown that the successful transition from insulin to sulfonylurea agents can be achieved in up to 90% of patients with NDM. However, most of the reports pertain to infants; the literature is limited regarding treatment of adults with NDM. We present our experience with a patient with permanent NDM, initially misdiagnosed as T1DM, who subsequently was successfully transitioned to oral sulfonylurea therapy after 37 years of insulin dependence.

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