Anti-obesity medications

​​​​​​​Nat Rev Endocrinol 2017; 14: 12–24. doi: 10.1038/nrendo.2017.122

A meta-analysis shows that although medications and lifestyle changes can both reduce the risk for type 2 diabetes in high-risk patients, only lifestyle modifications have a sustained effect.

Mottalib A et al. Curr Diab Rep 2017; 17: 92. doi: 10.1007/s11892-017-0918-8

Chatterjee S, Davies M, Khunti K. Am J Cardiovasc Drugs 2017; 1: 13–24. doi: 10.1007/s40256-017-0239-y

Kelly AS, Fox CK. Curr Diab Rep 2017; 17: 55. doi: 10.1007/s11892-017-0886-z

Pappachan JM, Viswanath AK. Curr Diab Rep 2017; 17: 4. doi: 10.1007/s11892-017-0828-9

The National Institute For Health and Care Excellence has issued an evidence summary to support use of the glucagon-like peptide-1 receptor agonist liraglutide in obese and overweight individuals with risk factors, such as dysglycemia.

Wilding JPH. Diabetologia 2017; 61: 265–272. doi: 10.1007/s00125-017-4288-1

Roberts CA et al. Acta Diabetol 2017; 54: 715–725. doi: 10.1007/s00592-017-0994-x

A patient affected by obesity discusses her experience of living with the disease and using many different weight loss approaches until finding a lifestyle program that was appropriate for her metabolism.

Taking the glucagon-like peptide-1 receptor agonist liraglutide does not increase patients’ risk for acute pancreatitis during more than 3 years of treatment, show two reports analyzing the LEADER and SCALE trials.

Targeting obese patients for weight-loss therapy according to their cardiometabolic status could much improve its effectiveness for diabetes prevention, say researchers.

Comment on: Liraglutide boosts preventive power of lifestyle intervention in prediabetes

Liraglutide enhances the positive effects of lifestyle intervention on weight loss and glycemic control in patients with prediabetes, show the 3-year outcomes of the SCALE Obesity and Prediabetes trial.

A patient with obesity, diabetes, and hypertension, discusses her experience with the onset of diabetes complicating obesity and with her frustration living with these diagnoses until finding an obesity medicine specialist physician who helped her lose weight and reverse her diabetes.

Khanna V, Kashyap SR. Curr Atheroscler Rep 2015; 17: 59. doi: 10.1007/s11883-015-0537-2