Type 1 diabetes and cardiovascular disease

A large systematic review and meta-analysis has identified racial/ethnic differences in the risk for complications and all-cause mortality among people with diabetes.

People who live with type 1 diabetes for more than 50 years are at least four times more likely to have cardiovascular disease than their diabetes-free peers, even when they have normal urinary albumin levels, study findings indicate.

Hyperinsulinemic hypoglycemia is associated with an increase in left ventricular ejection fraction among people with type 1 diabetes and healthy controls, research suggests.

Researchers have created and validated a cardiovascular disease risk tool that substantially improves risk prediction in people with type 1 diabetes and indicates that statins may not always be needed in younger members of this group.

Higher daily glucose variability is associated with greater aortic stiffness irrespective of average glucose levels, indicate findings from The Maastricht Study.

NHANES data indicate that glycemic and blood pressure control in people with diabetes in the USA has deteriorated over recent years, and lipid control has plateaued.

Adults with type 1 diabetes have a greater burden of cardiovascular and renal disease than those with type 2 diabetes, researchers report.

Analysis of the Women’s Health Study shows that diabetes is more strongly associated with risk for premature coronary heart disease than any other clinical risk factor or biomarker.

Adolescents with type 1 diabetes who are obese have a cardiorenal risk profile similar to that of their peers with type 2 diabetes, say researchers.

Absolute mortality rates are falling among younger people with type 1 diabetes, but excess mortality relative to the general population remains high and unchanged, show Scottish national registry data presented at the virtual 56th EASD Annual Meeting.

Australian adults with type 1 diabetes die almost 7 years earlier, on average, than their non-diabetic peers, with cardiovascular disease the most common cause of death, observational data presented at the virtual 56th EASD Annual Meeting show.

A prospective study has revealed that greater fasting glucose variability during young adulthood is independently associated with increased risk for coronary artery calcification progression in middle age.

People with diabetes who get their influenza vaccine are significantly less likely to have a fatal cardiovascular event or die from any cause than those who do not, shows a nationwide Danish study.

The excess risk for myocardial infarction associated with having diabetes may be greater in women than men, despite men having a higher frequency of events overall, shows research from the UK Biobank.

Findings from the SEARCH for Diabetes in Youth study suggest that diastolic dysfunction is prevalent among young adults with type 1 or type 2 diabetes, but those with type 2 diabetes have the highest risk.

Icosapent ethyl reduces the risk for first and total cardiovascular events in statin-treated patients with diabetes, suggests a subgroup analysis of the REDUCE-IT trial.

Resistant hypertension is linked to an increased risk for cardiovascular outcomes in type 1 diabetes, with renal damage accounting for a large part of the association, say researchers.

Researchers show that the presence of multiple cardiac autoantibodies is associated with subclinical myocardial dysfunction in people with type 1 diabetes.

The addition of rivaroxaban to aspirin results in a similar relative reduction in the risk for cardiovascular events among patients with stable atherosclerosis and a history of atherosclerotic disease regardless of whether or not they have diabetes, suggests a subgroup analysis of the COMPASS trial.

Older people with and without diabetes experience similar short-term improvements in exercise capacity following cardiac rehabilitation, but those with diabetes fare worse after 1 year, EU-CaRE study results suggest.