Prediabetes

Restricting eating to within a 10-hour daily window results in weight loss and metabolic benefits for people with metabolic syndrome, report researchers in Cell Metabolism.

A US survey suggests nearly one in five adolescents and one in four young adults has prediabetes and that the condition is linked to an unfavorable cardiometabolic risk profile.

Among individuals with multiple autoantibodies detected by screening, type 1 diabetes risk varies according to age, autoantibody type, and metabolic impairment, researchers report.

Prediabetes has no effect on the short-term mortality risk of older adults, suggests an analysis of the Atherosclerosis Risk in Communities study.

People who are trying to maintain weight loss with the help of electronic health records-based tracking tools do significantly better if they are given access to an online coach, shows a randomized trial.

Testing both glycated hemoglobin and fasting plasma glucose gives a more reliable hyperglycemia diagnosis than either on its own, but a follow-up screening test remains essential, say researchers.

A systematic review and meta-analysis published in The BMJ confirms that intake of omega-3 fats does not influence the risk for or progression of type 2 diabetes.

Meta-analysis data show that lifestyle modification interventions can reduce the risk for developing type 2 diabetes by more than a third in high-risk adults of South Asian origin.

Intensive antidiabetic treatment in adults with newly diagnosed type 2 diabetes slows the decline in beta-cell function, but this is not sustained after the treatment is stopped, show the results of the RISE adult medication study.

High-dose vitamin D supplementation does not significantly reduce the risk for developing type 2 diabetes among people with prediabetes, show D2d trial data.

Obese adults with prediabetes may need a longer-than-recommended course of behavioral weight loss treatment to optimize improvements in glycemic control, US researchers report.

Findings from the MET-REMODEL trial suggest that metformin treatment may aid regression of left ventricular hypertrophy among nondiabetic patients with coronary artery disease.

Lifestyle interventions to delay the onset of type 2 diabetes result in marked long-term reductions in cardiovascular disease and mortality, shows the 30-year follow-up of the Da Qing Diabetes Prevention Outcome Study.

Fifteen years of follow-up of the DPP trial shows that although people initially lost more weight with the intensive lifestyle intervention, those assigned to metformin did better at keeping the weight off in the long term.

The latest update from the UK’s National Health Service Diabetes Prevention Programme shows that persistence pays, and reveals weight loss and a reduction in glycated hemoglobin levels for people who have so far completed the intervention.

Agreement between five currently recommended definitions of intermediate hyperglycemia, or prediabetes, is poor, and their sensitivity for predicting type 2 diabetes is low, study findings indicate.

Insomnia bestows a degree of risk for type 2 diabetes on patients who already have prediabetes that “is similar to that conferred by traditional risk factors,” according to researchers.

The rate at which BMI changes throughout childhood and adolescence is significantly associated with adult hyperglycemia, independent of BMI level at specific time points, study findings indicate.

The results of the adult surgery study from the RISE consortium show that gastric banding has only a small effect on the deterioration of beta-cell function relative to metformin, despite causing markedly greater weight loss.

The RISE investigators have reported a continued lack of effect of early intensive therapy on beta-cell function decline in children with prediabetes or early type 2 diabetes.