Pediatric type 1 diabetes

A nationwide population-based study reveals a link between obesity in adolescence and an increased risk for type 1 diabetes in young adulthood.

Children born to mothers with autoimmune diseases have an elevated risk for mental disorders, with this risk persisting until early adulthood for those born to women with type 1 diabetes or rheumatoid arthritis, researchers report.

The Patient Health Questionnaire-9, which screens for depressive symptoms, underestimates suicide risk in adolescents and young adults with type 1 diabetes when compared with a validated suicide-specific measure, research shows.

Children with islet autoantibodies who spend more than 10% of their time with hyperglycemic glucose levels are highly likely to progress to clinical diabetes within the next year, show findings from the ASK study.

Young people with type 1 diabetes are at increased risk for hospitalization for acute complications at the time of transition from pediatric to adult care, say researchers.

Insulin sensitivity may be associated with the likelihood of partial remission in children and adolescents newly diagnosed with type 1 diabetes, regardless of C-peptide levels and BMI, research suggests.

Closed-loop control with the Cambridge hybrid system improves time in range in very young children with type 1 diabetes relative to sensor-augmented pump delivery over 16 weeks of use, researchers report.

The age at diagnosis of type 1 diabetes has decreased substantially across successive generations, show study findings presented at the virtual 57th EASD Annual Meeting.

Using a linear insulin to carbohydrate ratio to determine breakfast insulin requirements leads to significant differences in time in glycemic range and hypoglycemia rates when meal carbohydrate quantities vary, shows a study in children and young adults.

Rates of both type 2 and type 1 diabetes continue to rise in US children, show data from the SEARCH registry.

Assessing executive function and screening for disordered eating behaviors could help identify teenagers with type 1 diabetes who will benefit from interventions aimed at improving long-term outcomes, researchers report in Diabetic Medicine.

Children at increased genetic risk for type 1 diabetes are more likely to develop the condition if they have multiple, rather than single, islet autoantibodies present at the time of seroconversion, a combined analysis of prospective cohorts shows.

The presence of an eating disorder diagnosis significantly increases the risk for diabetic ketoacidosis and all-cause mortality in adolescents and young adults with type 1 diabetes, shows a population-based study.

Young children with recent onset type 1 diabetes display four unique glycated hemoglobin trajectories that may be influenced by parental psychosocial factors, US study findings indicate.

The Cambridge closed-loop insulin delivery system significantly improves glycemic control during 6 months of use by children and adolescents compared with standard insulin pump therapy, report the DAN05 investigators.

Use of the Omnipod 5 closed-loop insulin delivery system reduces diabetes distress and improves quality of life, particularly for the carers of children with type 1 diabetes, research shows.

The Omnipod 5 tubeless automated insulin delivery system improves glycemic outcomes of very young children with type 1 diabetes and the sleep of their caregivers, report researchers.

Use of continuous glucose monitoring within the first month of diagnosis is associated with an improvement in glycemic control among youth with type 1 diabetes, indicate findings from the 4T study.

A closed-loop system with an artificial intelligence component that rapidly detects when the user is eating a meal may offer a route towards fully closed-loop insulin delivery, shows a small crossover trial in adolescents and young adults.

Use of an insulin pump is not associated with better glycemic control than multiple daily injections among children and adolescents with type 1 diabetes, indicate real-world study results.