The latest update to the ADA and EASD hyperglycemia management consensus report places a strong emphasis on holistic, person-centered care for type 2 diabetes.

The ADA and KDIGO have produced a consensus statement on treating chronic kidney disease in people with diabetes.

“This suggests that the sexual response in women may be more affected by psychosocial aspects rather than metabolic control or complications of diabetes,” commented Blair. medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2022 Springer Healthcare Ltd, part of the Springer Nature Group ADA Scientific Sessions; New Orleans, Louisiana: 3–7 June 2022 (abstract 86-OR) ADA Scientific Sessions; New Orleans, Louisiana: 3–7 June 2022 (abstract 87-OR

“The impact of the program on patient satisfaction, quality of life, and total cost of care is substantial and holds significant promise for large populations suffering from metabolic disease globally.” medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2022 Springer Healthcare Ltd, part of the Springer Nature Group ADA Scientific Sessions; New Orleans, Louisiana: 3–7 June 2022

Caplan said that if other mechanisms besides GLP-1 signaling prove to have a powerful effect on fat mass regulation, “then we truly have the ability – as with hypertension, as with diabetes, as with other chronic diseases – to be able to hit it from multiple different mechanisms.” medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2022 Springer Healthcare Ltd, part of the Springer Nature Group N Engl J Med 2022; doi:10.1056/NEJMoa2206038 ADA Scientific Sessions; New Orleans, Louisiana: 3–7 June 2022

Nevertheless, they observe that dulaglutide’s safety profile in the youths was in line with that in adults and conclude that the medication is “potentially promising” for this younger age group. medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2022 Springer Healthcare Ltd, part of the Springer Nature Group N Engl J Med 2022; doi:10.1056/NEJMoa2204601 ADA Scientific Sessions; New Orleans, Louisiana: 3–7 June 2022

medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2022 Springer Healthcare Ltd, part of the Springer Nature Group ADA Scientific Sessions; New Orleans, Louisiana: 3–7 June 2022

She suggested that, while people with GK-MODY who only have one GK mutation may not require this level of treatment, dorzagliatin shows promise for homozygous individuals with GK-MODY and others who develop more severe symptoms. medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2022 Springer Healthcare Ltd, part of the Springer Nature Group ADA Scientific Sessions; New Orleans, Louisiana: 3–7 June 2022

Time in tight range (3.9–7.8 mmol/L, 70–140 mg/dL) improved by an average of 15.8% between the groups and there was no increase in hypoglycemia. medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2022 Springer Healthcare Ltd, part of the Springer Nature Group ADA Scientific Sessions; New Orleans, Louisiana: 3–7 June 2022

She concluded: “One of those things that we now know is that minimizing variability overnight is probably going to have the best impact on how people feel.” medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2022 Springer Healthcare Ltd, part of the Springer Nature Group ADA Scientific Sessions; New Orleans, Louisiana: 3–7 June 2022

Just one adverse event, of a “mild” rise in liver enzymes post-infusion, was considered related to the treatment. medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2022 Springer Healthcare Ltd, part of the Springer Nature Group ADA Scientific Sessions; New Orleans, Louisiana: 3–7 June 2022

“We are planning to do a randomized control trial to confirm that SGLT2 inhibitors can lower plasma glucose in these patients,” he explained. medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2022 Springer Healthcare Ltd, part of the Springer Nature Group ADA Scientific Sessions; New Orleans, Louisiana: 3–7 June 2022

Independent of TIR, there was also a 63% reduction in hospital admissions related to hyperglycemia or diabetic ketoacidosis and an 85% reduction in paramedic callouts in those using the monitor. medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2022 Springer Healthcare Ltd, part of the Springer Nature Group ADA Scientific Sessions; New Orleans, Louisiana: 3–7 June 2022

This was in line with previous research from the team, which found approximately one additional major lower extremity amputation per 1000 people in the Diabetes Belt compared with the surrounding counties. medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2022 Springer Healthcare Ltd, part of the Springer Nature Group ADA Scientific Sessions; New Orleans, Louisiana: 3–7 June 2022

In response to a question, Pieber said that participants were monitored for 4 days after the double and triple icodec doses, during which recurrent hypoglycemia episodes were rare and mild, and “easily compensated with oral carbohydrates.” medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2022 Springer Healthcare Ltd, part of the Springer Nature Group ADA Scientific Sessions; New Orleans, Louisiana: 3–7 June 2022

“Social constructs on stress management may explain the observed gender differences and suggest taking a gender-based differential approach when addressing hypoglycemia,” conclude the researchers. medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2022 Springer Healthcare Ltd, part of the Springer Nature Group ADA Scientific Sessions; New Orleans, Louisiana: 3–7 June 2022

It’s not enough to tell them to remember to take their medications.” medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2022 Springer Healthcare Ltd, part of the Springer Nature Group ADA Scientific Sessions; New Orleans, Louisiana: 3–7 June 2022

The monitoring rate was only slightly higher among people with neuropathy, at 10.1% and 3.7% for those seen in primary care and endocrinology, respectively. medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2022 Springer Healthcare Ltd, part of the Springer Nature Group ADA Scientific Sessions; New Orleans, Louisiana: 3–7 June 2022

“Our findings suggest that the presence of any liver fat may be abnormal,” concluded Le, adding that an MRS cutoff of around 2% may be optimal for defining non-alcoholic fatty liver disease. medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2022 Springer Healthcare Ltd, part of the Springer Nature Group ADA Scientific Sessions; New Orleans, Louisiana: 3–7 June 2022

“These long-term data provide evidence of the durability of the Omnipod 5 for safely and effectively improving outcomes in very young kids with type 1 diabetes and also alleviating the burden of daily diabetes management,” concluded DeSalvo. medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2022 Springer Healthcare Ltd, part of the Springer Nature Group ADA Scientific Sessions; New Orleans, Louisiana: 3–7 June 2022