Diabetes complications and comorbidities: Ketoacidosis

Neither the rate of administration nor the sodium chloride content of replacement fluids given to children with diabetic ketoacidosis influences their neurologic outcomes, show the results of the PECARN DKA FLUID Study.

Students with type 1 diabetes report increased difficulties with managing their condition when they start at university, with consequences for glycemic control and acute complications.

Children are less likely to present with diabetic ketoacidosis at the time of type 1 diabetes diagnosis if they previously had regular access to a healthcare provider, research published in CMAJ suggests.

Findings from a population-based study indicate that insulin pump use is associated with reduced risks for severe hypoglycemia and diabetic ketoacidosis in children, adolescents, and young adults with type 1 diabetes.

Sotagliflozin may be an effective add-on therapy to insulin for patients with type 1 diabetes, but the benefits are less clear in a young adult population, suggest the results of two studies presented at the EASD annual meeting in Lisbon, Portugal.

Dapagliflozin is a promising adjunct treatment to insulin for patients with type 1 diabetes, suggest phase III trial results presented at the EASD annual meeting in Lisbon, Portugal, and published simultaneously in The Lancet Diabetes & Endocrinology.

Results of the inTandem3 study suggest that adding the sodium–glucose cotransporter 1 and 2 inhibitor sotagliflozin to insulin treatment improves glycemic control among patients with type 1 diabetes, but at the cost of an increased risk for ketoacidosis.

A study has found that children with diabetic ketoacidosis at the diagnosis of type 1 diabetes have poor long-term glycemic control, independent of established demographic and socioeconomic risk factors.

Research findings indicate that patients with type 2 diabetes may have an increased risk for diabetic ketoacidosis when they begin treatment with a sodium–glucose cotransporter 2 inhibitor.

Almost two-thirds of children hospitalized with diabetic ketoacidosis develop acute kidney injury within 24 hours of hospitalization, study findings indicate.

Researchers report two cases of children with severe and irreversible neurologic damage caused by complications at the time of neonatal diabetes diagnosis, highlighting the need for increased awareness of the condition.

A large survey highlights that patients with type 1 diabetes are poorly compliant with self-monitoring their ketone levels when needed, leading the researchers to urge better education on the subject.

Mortality rates are high among adolescents and young adults with type I diabetes, with more than half caused by acute or chronic complications, researchers report.