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Type 2 diabetes and cardiovascular disease

Highlights

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05-31-2018 | Obesity | Highlight | News

Yet more evidence against metabolically healthy obesity

Another two large studies have demonstrated that people who appear to be in good health despite being obese do not remain so for long.

Chocolate

05-24-2018 | Diet | Article

Intake of cocoa products and risk of type-2 diabetes: The multiethnic cohort

Maskarinec G et al. Eur J Clin Nutr 2018. doi: 10.1038/s41430-018-0188-9

UK nutrition guidelines: A fresh approach

05-22-2018 | Nutritional management | Editorial | Article

UK nutrition guidelines for the prevention and management of diabetes: An update for primary care

Advisory Board member Pamela Dyson underlines the key features for healthcare professionals working in diabetes education, diabetes management, type 2 diabetes prevention, and cardiovascular risk reduction.

Person holding sweeteners

05-15-2018 | Diet | Article

Glycemic impact of non-nutritive sweeteners: A systematic review and meta-analysis of randomized controlled trials

Nichol AD, Holle MJ, An R. Eur J Clin Nutr 2018. doi: 10.1038/s41430-018-0170-6

New Content Item

05-10-2018 | Specific populations | Highlight | News

Women bear brunt of diabetes effect on atherosclerosis mortality

An individual patient data meta-analysis confirms that diabetes increases the likelihood for people dying of atherosclerotic disease, with women the worst affected.

Blood pressure

04-27-2018 | Nephropathy | Highlight | News

Renal risk associated with intensive BP treatment in type 2 diabetes

Research shows that intensive blood pressure control increases the risk for new-onset chronic kidney disease, particularly in patients with type 2 diabetes, creating a potential treatment dilemma.

Heart_pills

04-24-2018 | Cardiovascular disorders | Highlight | News

Patients with type 2 diabetes and CVD may receive suboptimal treatment

Specialist physicians and antidiabetic medications reported to confer cardiovascular benefit are being underutilized by patients with type 2 diabetes and cardiovascular disease, US study data show.

Pills

04-03-2018 | Alogliptin | Highlight | News

Support for alogliptin as add-on therapy for type 2 diabetes

Adding the dipeptidyl peptidase-4 inhibitor alogliptin to metformin and sulfonylurea treatment may improve glycemic control in patients with type 2 diabetes and high cardiovascular risk, a post-hoc analysis of the EXAMINE trial suggests.

Heart and stethoscope

03-12-2018 | Canagliflozin | Highlight | News

CANVAS analysis supports SGLT2 inhibitor benefits for HF

The latest analysis of the CANVAS trial indicates that the cardiovascular benefits of canagliflozin in patients with type 2 diabetes may be greatest in those with concomitant heart failure.

Kidneys

03-02-2018 | Prediabetes | Highlight | News

Prediabetes goes hand in hand with cardiovascular and renal risk factors

Data from the US NHANES show that a high proportion of adults with prediabetes also have cardiovascular and renal risk factors.

Pill in hand (symbolic image with model)

02-13-2018 | Older adults | Editorial | Article

Does setting treatment targets risk the overtreatment of type 2 diabetes in older patients?

The drive to achieve lower HbA1c targets in older patients is not without concern or risk. Our UK Board address concerns highlighted by recent trials and discuss whether current guidelines do enough to mitigate the risks of overtreatment.

Editorial Board member Jay Shubrook follows up with treatment individualization specialist David Strain on the treatment challenges presented by older adults, and the implications for tailoring hypertension therapy in this diverse population (11:08).



Learning points include:

  • The rationale for emphasizing quality over quantity of life in certain subsets of the elderly patient population.
  • The importance of incorporating understanding of key comorbidities into treatment planning, including:
    • Left ventricular and/or diastolic dysfunction
    • Chronic kidney disease 
    • Benign prostatic hyperplasia
    • Heart failure
  • Single/multi-agent therapies capable of targeting hypertension and its comorbidities.
  • The importance of early renal function testing in older adults initiated on treatments for hypertension and its comorbidities.
  • Understanding renal impairment risks in vulnerable adults treated with angiotensin-converting-enzyme (ACE) inhibitors in patients.
  • Understanding the relative risk of hyponatremia with generally well-tolerated treatments like as thiazide diuretics.
  • Best practice for avoiding adverse drug events in the acute setting.
  • The challenges associated with treating concomitant heart failure in older adults.

« Video 4: Individualization of diabetes treatment: Considerations for frail, elderly patients with heart failure

Editorial Board member Jay Shubrook talks to treatment individualization specialist David Strain about the treatment challenges presented by older adults, and the implications for tailoring hypertension therapy in this diverse population (11:40).


Learning points include:

  • The ways in which older adults are physiologically distinct from other populations and considerations for appropriate care based on anticipated lifestyle.
  • Expectations for systolic and diastolic blood pressure changes in older adults as well as the impacts they have on cardiovascular health.
  • The importance of specific measures including: pulse pressure, arterial compliance.
  • Risk factors associated with low diastolic blood pressure (<75mmHg) and prospective antihypertensive treatment strategies that may mitigate such risks.

 

« Video 3: When to intervene in patients with diabetes and high blood pressure?



Video 5: Diabetes and blood pressure in the elderly: Which medications to use when; tips for achieving target »

 

Editorial Board member Jay Shubrook and Advisory Board member Robert Chilton get together once more to discuss best practice tips for identifying and treating hypertension in patients with pre-existing diabetes (12:17).



Learning points include:

  • Strategies to avoid common pitfalls when performing blood pressure measurements.
  • The importance of the blood pressure measurements in determining the risk of cardiovascular events.
  • The benefits of dual-action and preload-targeted therapies in hypertensive patients.
  • Why potassium levels are an important factor to consider before initiating treatment.

« Video 2: Why aren't we reaching blood pressure goals, despite the raised target?



Video 4: Individualization of diabetes treatment: Considerations for frail, elderly patients with heart failure »

In the wake of the revised blood pressure targets, recommended by the American Diabetes Association's 2017 Position Statement and 2018 Standards of Care, Editorial Board member Jay Shubrook and Advisory Board member Robert Chilton discuss clinical approaches to get hypertensive diabetes patients to target more consistently (12:29).


Learning points include:

  • The atherogenic risk posed by diabetes and why blood pressure measurements from the arm-alone may not be sufficient to evaluate the threat in all patients.
  • The benefits and drawbacks of the medication classes indicated for hypertension treatment, such as:
    • Diuretics
    • β-blockers
    • Calcium channel blockers
  • The impact and rationale for targeting blood pressures lower than those indicated in the ADA position statement. 

« Video 2: What are the current recommendations for managing high blood pressure in diabetes patients?



Video 3: When to intervene in patients with diabetes and high blood pressure? »

Lori Berard / International Diabetes Federation

11-13-2017 | Specific populations | Interview | Article

Women and diabetes - our right to a healthy future

Editorial Board member Lori Berard addresses 2017's World Diabetes Day theme, providing her insights on the key considerations for managing diabetes in women (9:51).

Hypoglycemia

11-02-2017 | Hypoglycemia | Practical approach | Article

Practical approaches to diagnosing, treating, and preventing hypoglycemia in diabetes

Using a patient-centered care approach, the authors detail how to work in partnership with a patient to prevent hypoglycemia through evidence-based management of the disease and appropriate education.

Counting on hands (one to five)

08-22-2017 | Primary care | View from the clinic | Article

Five things you can do to make your diabetes visits more efficient

Diabetes check-ups can be multifaceted and time-consuming. Editorial Board member and Family Physician, Jay Shubrook, presents his practical recommendations for making the most of your patient visits.