Pediatric diabetes and diabetic complications

Researchers have identified a marked increase in the proportion of children and adolescents who have diabetic ketoacidosis at the point of type 1 diabetes diagnosis during the COVID-19 pandemic.

Continuous glucose monitoring is well accepted and reduces time in hypoglycemia among older individuals with type 1 diabetes, report researchers in JAMA.

Asymptomatic celiac disease is a frequently occurring comorbidity in people with type 1 diabetes, and transitioning to a gluten-free diet may increase postprandial glycemic variability, researchers report.

A major study of children from three continents suggests that diabetic ketoacidosis remains unacceptably high among those newly identified with type 1 diabetes and shows few signs of improving.

Age at type 1 diabetes diagnosis does not appear to affect glycemic control and comorbidity once disease is established, but important differences occur between age groups at the time of diagnosis, US study data show.

The presence of diabetes distress and body dissatisfaction may warn of a high risk for disordered eating in adolescents with type 1 diabetes, show data from the Diabetes MILES Youth–Australia study.

Adolescents who undergo bariatric surgery do not as a rule experience resolution of mental health problems, say researchers.

People with type 1 diabetes using the Tandem Control-IQ hybrid closed-loop insulin delivery system spent significantly more time within their target blood glucose range than people using a sensor-augmented insulin pump during 6 months of use in the iDCL trial.

Implementing a nursing protocol that includes point-of-care testing at triage reduces the time to diabetic ketoacidosis diagnosis and the number of unnecessary intravenous placements in the pediatric emergency department, say researchers.

A retrospective analysis of clinical trial data indicates that regular eye examinations may not always be necessary for people younger than 18 years of age with type 1 diabetes, despite current recommendations to the contrary.

Approximately one-third of adolescents and young adults with type 1 diabetes display disturbed eating behavior that may be linked to worsening glycemic control and increasing depressive symptoms over time, research shows.

Researchers report that having type 1 diabetes may affect children’s brain growth and cognitive development, with persistent hyperglycemia the most likely culprit.

Young people who deliberately omit insulin to either lose weight or prevent weight gain report worse psychosocial functioning, particularly depressive symptoms, than those who have never skipped a dose for this reason, study data show.

Diabetes distress is more common than depression in adolescents with diabetes and is significantly associated with less frequent blood glucose monitoring and higher glycated hemoglobin levels, study findings indicate.

Shared medical appointments may help adolescents with type 1 diabetes to reduce family conflict and improve their depressive symptoms, show data presented at the 79th ADA Scientific Sessions in San Francisco, California, USA.

Children with type 1 diabetes are more likely than their non-diabetic peers to seek primary care for a number of specific conditions in the year before their diagnosis, which could aid detection before the onset of diabetic ketoacidosis, say researchers.

Patients with type 1 diabetes may develop multiple complications even before they reach adulthood, shows an analysis of the SEARCH for Diabetes in Youth Study.

Insulin manipulation, the practice of deliberately under- or overdosing insulin, is strongly associated with psychiatric comorbidity in children and young adults with type 1 diabetes, Austrian research shows.

The Tandem Basal-IQ predictive low-glucose suspend insulin delivery system significantly reduces the proportion of time adults and children spend in hypoglycemia during 24-hour usage, show findings from the randomized crossover PROLOG trial.

Having an albumin-to-creatinine ratio at the upper end of the normal range predicts microalbuminuria and cardiovascular risk in adolescents with type 1 diabetes, say the AdDIT investigators.