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08-14-2019 | Gestational diabetes | News

Metformin exposure during pregnancy may impact postnatal growth trajectory

Infants born to mothers with gestational diabetes treated with metformin have lower birthweight, but experience accelerated postnatal growth and have higher BMI in childhood, compared with those whose mothers were treated with insulin, suggest findings from a meta-analysis.

08-08-2019 | Continuous glucose monitoring | News

Pros and cons of CGM described by parents of children with diabetes

Continuous glucose monitoring offers many benefits to the families of young children with type 1 diabetes but also a number of challenges that cannot always be overcome, show results of a qualitative analysis conducted in the USA.

07-24-2019 | Children | News

Puberty linked to glucose variability in type 1 diabetes

Changes in glucose levels through the day and night in young people with type 1 diabetes may differ according to whether or not they have gone through puberty, research suggests.

07-22-2019 | Children | News

Children with type 1 diabetes fare worse than peers in health, education

Children with type 1 diabetes have worse health outcomes and are more likely to miss school and have special educational needs than their nondiabetic peers, show results of a large study conducted in Scotland.

07-02-2019 | Retinopathy | News

Young diabetes patients may undergo needless retinopathy examinations

A retrospective analysis of clinical trial data indicates that regular eye examinations may not always be necessary for people younger than 18 years of age with type 1 diabetes, despite current recommendations to the contrary.

06-18-2019 | Hyperglycemia | ADA 2019 | News

Hyperglycemia may impact brain development in children with type 1 diabetes

Researchers report that having type 1 diabetes may affect children’s brain growth and cognitive development, with persistent hyperglycemia the most likely culprit.

06-10-2019 | Prediabetes | ADA 2019 | News

RISE adult medication results highlight disparity with youth with diabetes

Intensive antidiabetic treatment in adults with newly diagnosed type 2 diabetes slows the decline in beta-cell function, but this is not sustained after the treatment is stopped, show the results of the RISE adult medication study.

06-09-2019 | Children | ADA 2019 | News

TODAY2 confirms steep type 2 diabetes trajectory in youth

The latest analysis from the observational follow-up of the TODAY study participants shows rapid accumulation of cardiovascular risk factors and diabetes complications in people who were diagnosed with type 2 diabetes in youth.

05-31-2019 | Children | News

High variability in insulin needs complicates diabetes management in young children

Children with type 1 diabetes who are aged 6 years or younger have significantly more variability in their insulin needs than adolescents or adults, shows an analysis of closed-loop data.

05-28-2019 | Children | Highlight | News

Maternal education has major impact on glycemic control in children

Researchers report that women’s educational attainment is strongly associated with the glycated hemoglobin levels of their children with type 1 diabetes.

05-10-2019 | Psychosocial care | Highlight | News

Family conflict key factor in poor glycemic control among young insulin users

Factors associated with poor glycemic control in children with type 1 diabetes generally vary according to the insulin regimen used, but family conflict over diabetes management universally impacts all insulin users, US researchers report.

04-29-2019 | Liraglutide (T2DM) | Highlight | News

Ellipse trial: Liraglutide expands treatment options for pediatric type 2 diabetes

The Ellipse investigators report improved glycemic control at the price of early and mostly mild gastrointestinal events in children and adolescents with type 2 diabetes.

04-04-2019 | Insulin pumps | Highlight | News

Randomized trial questions superiority of insulin pumps over injections in children

Insulin pumps and multiple daily injections deliver similar glycemic control and safety profiles when allocated alongside education and support at the point of type 1 diabetes diagnosis, say researchers.

03-25-2019 | Artificial pancreas systems | News

Real-world data highlight closed-loop frustrations for youth users

System problems and irritations lead to nearly two in five children abandoning use of closed-loop insulin delivery in a real-world setting, researchers have reported.

02-26-2019 | Psychosocial care | ATTD 2019 | News

CGM at diabetes diagnosis improves family psychosocial outcomes

Giving children continuous glucose monitoring from the point of diabetes diagnosis gives their caregivers greater confidence to manage hypoglycemia and reduces their diabetes-related distress, shows a randomized trial.

02-19-2019 | Ketoacidosis | Highlight | News

Data highlight opportunities to diagnose type 1 diabetes before DKA onset

Children with type 1 diabetes are more likely than their non-diabetic peers to seek primary care for a number of specific conditions in the year before their diagnosis, which could aid detection before the onset of diabetic ketoacidosis, say researchers.

02-05-2019 | Children | Highlight | News

Children with type 1 diabetes do not suffer academically

Type 1 diabetes has no significant impact on standardized test scores in mathematics and reading for children in grades 2 to 8, show results of a study of Danish public school children.

02-01-2019 | Artificial pancreas systems | News

Support for hybrid closed-loop insulin delivery in young children

Home use of day and night hybrid closed-loop insulin delivery using the Cambridge model predictive control algorithm is feasible in children aged 1–7 years with type 1 diabetes, researchers report.

01-31-2019 | Glycemic control | News

Glycemic control in type 1 diabetes not improving in the USA

Just one-fifth of adults, and an even lower proportion of children and adolescents, with type 1 diabetes in the T1D Exchange registry currently meet the ADA target for glycemic control, US researchers report.

11-28-2018 | Epidemiology | News

Childhood type 1 diabetes incidence still rising in Europe

The incidence of childhood type 1 diabetes continues to increase across Europe, with the number of cases potentially doubling in the next 20 years, an analysis of 25 years of EURODIAB registry data shows.

10-24-2018 | Obesity | News

BMI trajectory linked to hyperglycemia risk irrespective of BMI level

The rate at which BMI changes throughout childhood and adolescence is significantly associated with adult hyperglycemia, independent of BMI level at specific time points, study findings indicate.

10-22-2018 | Mental health | Highlight | News

Insulin manipulation strongly linked to psychiatric comorbidity

Insulin manipulation, the practice of deliberately under- or overdosing insulin, is strongly associated with psychiatric comorbidity in children and young adults with type 1 diabetes, Austrian research shows.

10-10-2018 | Risk factors | EASD 2018 | News

Weight gain since childhood imposes high diabetes risk

The risk for type 2 diabetes in overweight people is higher in those who gained weight after the age of 10 years than in those who were already overweight at that time, researchers report.

10-09-2018 | Children | EASD 2018 | News

RISE pediatric findings consistent over longer term

The RISE investigators have reported a continued lack of effect of early intensive therapy on beta-cell function decline in children with prediabetes or early type 2 diabetes.

10-05-2018 | Obesity | News

Preschool weight gain confers highest risk for teenage obesity

Almost all children who are obese by the age of 3 years remain obese into adolescence, shows a study in The New England Journal of Medicine.

10-04-2018 | Artificial pancreas systems | EASD 2018 | News

‘Gold standard’ trial tests closed-loop delivery across the age spectrum

A randomized trial demonstrates the efficacy of closed-loop insulin delivery in a wide range of patients with poorly controlled type 1 diabetes.

09-21-2018 | Pregnancy | News

High and low gestational weight gain increase cardiometabolic risk in children

Both excessive and inadequate weight gain during pregnancy are associated with significantly increased cardiometabolic risk factors among the children at age 7 years, researchers from Hong Kong report.

09-10-2018 | Gestational diabetes | News

Gestational diabetes has minimal impact on childhood obesity risk

Maternal BMI prior to and during early pregnancy has a greater impact than gestational diabetes and hypertension, and pre-eclampsia on the risk for increased BMI in childhood, study findings indicate.

08-27-2018 | Adolescents | News

Ethnicity influences reversibility of dysglycemia in obese children

Impaired glucose tolerance in obese youths frequently reverts to normal, although the chances of this happening are strongly influenced by ethnicity, researchers report in The Lancet Child & Adolescent Health.

08-22-2018 | Insulin pumps | News

Predictive insulin-suspend algorithm cuts hypoglycemia without consequent hyperglycemia

The Tandem Basal-IQ predictive low-glucose suspend insulin delivery system significantly reduces the proportion of time adults and children spend in hypoglycemia during 24-hour usage, show findings from the randomized crossover PROLOG trial.

08-13-2018 | Insulin degludec | News

Fixed degludec–aspart co-formulation shows promise in pediatric diabetes

The fixed soluble co-formulation of insulin degludec/insulin aspart offers similar glycemic control to insulin detemir when each are combined with mealtime insulin aspart in children with type 1 diabetes, research shows.

08-10-2018 | Cardiovascular outcomes | Highlight | News

Earlier onset of type 1 diabetes associated with increased risk for adverse outcomes

Patients with type 1 diabetes diagnosed before the age of 10 years have a higher risk for cardiovascular complications and a shorter life expectancy than those who develop the disease at an older age, study results published in The Lancet suggest.

07-31-2018 | Insulin pumps | News

Pros and cons of insulin pumps highlighted in young type 1 diabetes patients

Continuous subcutaneous insulin infusion therapy significantly lowers glycated hemoglobin levels in young people with type 1 diabetes, but at the cost of an increased risk for diabetic ketoacidosis during the first year, UK researchers report.

07-13-2018 | Pathophysiology | News

Ethnicity, BMI modify risk for progression toward type 1 diabetes

Findings from the Type 1 Diabetes TrialNet Study Group show both independent and interacting effects of ethnicity, age, and BMI on progression toward type 1 diabetes in at-risk people.

06-26-2018 | Pathophysiology | ADA 2018 | News

RISE: Early insulin does not slow beta cell decline in youth with type 2 diabetes

The RISE trial investigators have found that increased insulin resistance and hyperresponsive beta cells may explain the rapid progression of type 2 diabetes in children.

06-25-2018 | Type 1 diabetes | ADA 2018 | News

Markers of progression to type 1 diabetes proposed

Changes in the gut microbiome, microRNAs, glucose response curves, and pancreas volume may all be associated with progression to type 1 diabetes, reported researchers at the ADA’s 78th Scientific Sessions in Orlando, Florida, USA.

06-24-2018 | Pathophysiology | ADA 2018 | News

ASK finds islet autoantibodies in 1% of unselected children

The ASK study findings show that around 1% of children in the general population are at high risk for diabetes, and the majority of these have no family history of the condition.

06-24-2018 | Continuous glucose monitoring | ADA 2018 | News

Eversense glucose monitor accurate and popular for adolescent patients

Researchers have reported good accuracy, durability, and acceptability of the Eversense continuous glucose monitoring system in a group of primarily pediatric patients.

06-23-2018 | Children | ADA 2018 | News

Pubertal status affects glycemic variability in children with type 1 diabetes

Prepubertal children with type 1 diabetes have greater glycemic variability than those who are pubertal or postpubertal, researchers have reported at the ADA’s 78th Scientific Sessions.

06-13-2018 | Ketoacidosis | Highlight | News

Fluid management strategy absolved of neurologic injury blame in childhood DKA

Neither the rate of administration nor the sodium chloride content of replacement fluids given to children with diabetic ketoacidosis influences their neurologic outcomes, show the results of the PECARN DKA FLUID Study.

05-24-2018 | Adolescents | Highlight | News

Insulin, metformin remain most used treatments for type 2 diabetes in youths

The majority of adolescents and young adults with type 2 diabetes are still being treated with metformin and/or insulin, despite a growing number of medications being available for adults, US study data show.

05-09-2018 | Diet | Highlight | News

Study suggests benefits of very low carbohydrate intake in type 1 diabetes

A study of type 1 diabetes patients voluntarily following a very-low-carbohydrate diet suggests that the approach could help to achieve excellent control of blood glucose levels.

04-13-2018 | Healthcare systems | News

Regular healthcare access may reduce children’s DKA risk at diabetes diagnosis

Children are less likely to present with diabetic ketoacidosis at the time of type 1 diabetes diagnosis if they previously had regular access to a healthcare provider, research published in CMAJ suggests.

04-05-2018 | Obesity | Highlight | News

Weight loss before puberty may mitigate excess diabetes risk associated with childhood overweight

Children who are overweight only have an increased risk for type 2 diabetes in adulthood if they remain overweight beyond the age of 13 years, according to the results of a large Danish study.

03-09-2018 | Glycemic control | News

Early glycemic control sets life course for type 1 diabetes patients

The degree of glycemic control that patients with type 1 diabetes achieve during the first 4 to 5 years after diagnosis may set the long-term pattern, research suggests.

03-07-2018 | Children | News

Racial and ethnic minority youths predisposed to poor diabetes prognosis

African–American and Hispanic adolescents are more likely than their non-Hispanic White peers to present with characteristics associated with poor long-term prognosis when they are first diagnosed with type 1 diabetes, research suggests.

02-21-2018 | Insulin pumps | News

Tubeless insulin pumps offer durable alternative to MDI in adolescents

Tubeless insulin pump use can provide long-term improvements in glycemic control at a lower total daily dose of insulin compared with multiple daily injections, show results of a retrospective study among children and young adults with type 1 diabetes.

02-15-2018 | Glycemic control | News

Household food insecurity linked to poor glycemic control

Young patients with type 1 diabetes who have inadequate access to nutritional food are more likely to have poor glycemic control than those from food-secure households, researchers report.

01-30-2018 | Transitions of care | News

SEARCH highlights flaws in transfer from pediatric to adult diabetes care

US researchers call for tailored clinical programs and policies to improve the transition from pediatric to adult care, and thus prevent worsening glycemic control, in young adults with type 2 diabetes.

01-25-2018 | Obesity | News

More evidence for ‘social contagion’ in obesity

Researchers have found that the bodyweights of family members of military personnel tend to change to match what is predominant in their area of posting.

01-09-2018 | Hypoglycemia | News

Weight-based glucose best for tackling hypoglycemia in pump users

Taking a weight-based dose of glucose resolves hypoglycemia more effectively than taking a standard fixed dose for type 1 diabetes patients using an insulin pump, show the results of a randomized crossover trial.

01-03-2018 | Diabetes prevention | News

Hydrolyzed infant milk does not modify type 1 diabetes risk

Limiting the exposure of high-risk infants to foreign intact protein does not reduce their risk for developing type 1 diabetes, show the results of the TRIGR study.

12-21-2017 | Mental health | News

Psychiatric morbidity risk high after childhood diabetes diagnosis

Results of a population-based study suggests that children may be vulnerable to developing psychiatric disorders in the years following a diagnosis of type 1 diabetes.

12-18-2017 | Hypoglycemia | News

Severe hypoglycemia risk remains high years after previous episode in children with diabetes

The risk of having a repeat episode of severe hypoglycemia is elevated for at least 4 years after a previous episode in children with type 1 diabetes, although the risk is highest during the first year, researchers report.

12-14-2017 | Hypoglycemia | News

Automatic insulin pump suspension reduces hypoglycemia in adolescents with diabetes

Children and adolescents with type 1 diabetes using a predictive low-glucose management system have less hypoglycemia and fewer hypoglycemic events than those managed using sensor-augmented pump therapy alone, according to a 6-month trial.

10-31-2017 | Children | News

Type 1 diabetes autoimmunity highlights celiac disease risk

A study in children has highlighted a possible relationship between type 1 diabetes and celiac disease and provides insights into the preclinical stages of these conditions.

10-10-2017 | Insulin pumps | News

Real-world data support reduced hypoglycemia risk in young pump users

Findings from a population-based study indicate that insulin pump use is associated with reduced risks for severe hypoglycemia and diabetic ketoacidosis in children, adolescents, and young adults with type 1 diabetes.

08-10-2017 | Children | News

Genetics support childhood adiposity and type 1 diabetes link

Genetic variants associated with childhood body mass index correlate with the risk for type 1 diabetes, suggests an analysis of genome-wide association studies.

07-26-2017 | Adolescents | News

Poor lifestyle intervention adherence may dilute effectiveness in youths with type 2 diabetes

Session attendance was only moderate and self-monitoring very poor in youths with type 2 diabetes who participated in the TODAY lifestyle programme, an analysis shows.

07-12-2017 | Ketoacidosis | News

Ketoacidosis at type 1 diabetes diagnosis predicts poor long-term glycemic control

A study has found that children with diabetic ketoacidosis at the diagnosis of type 1 diabetes have poor long-term glycemic control, independent of established demographic and socioeconomic risk factors.

07-04-2017 | Metformin | News

Mixed results from randomised trial of metformin in obese children

A randomized controlled trial shows some benefit of metformin treatment in prepubertal children with obesity, but not in pubertal participants.

06-23-2017 | Obesity | News

Poor-quality evidence for lifestyle interventions in overweight children

Cochrane reviewers have assessed the effectiveness of behavior-changing interventions in overweight and obese children, finding an indication of benefit but based on mostly low-quality evidence.

06-13-2017 | Pregnancy | ADA 2017 | News

HAPO FUS shows persistent ill effects of maternal diabetes

The HAPO FUS investigators have reported that the increased risk for adiposity in the babies of women with gestational diabetes persists through to later childhood.

06-11-2017 | Obesity | ADA 2017 | News

Diabetes risk of childhood overweight may be reversible

A study of Danish men suggests that the increased risk for diabetes associated with being overweight in childhood may be reversed if people lose their excess weight by young adulthood.

06-11-2017 | Disordered eating | ADA 2017 | News

Disordered eating common among youths with diabetes

Findings from the SEARCH for Diabetes in Youth study reveal high rates of disordered eating behaviors among children and young adults with diabetes.

05-26-2017 | Children | News

Celiac disease warrants growth monitoring in children with diabetes

Researchers have highlighted the importance of monitoring nutrition in children with type 1 diabetes who also have celiac disease, finding that the comorbidity may adversely affect growth.

05-26-2017 | Children | News

Glycemic control may improve QoL in youths with type 1 diabetes

Lower levels of glycated hemoglobin are associated with better diabetes-specific health-related quality of life among young people with type 1 diabetes, researchers report.

05-11-2017 | Children | News

Fatty acids consumed during breastfeeding could protect against type 1 diabetes

Fatty acids derived from fish and consumed during breastfeeding may protect against the development of type 1 diabetes-associated autoimmunity, researchers report.

04-13-2017 | Children | News

Immunological, genetic factors associated with rapid progression to type 1 diabetes

Study results suggest that autoantibody-positive children who progress rapidly to type 1 diabetes have higher antibody titers and distinct genetic characteristics compared with those who develop the disease more slowly or do not progress to diabetes.

04-13-2017 | Epidemiology | News

Early-onset diabetes on the rise, but hope for reduced long-term impact

Two independent studies published in The New England Journal of Medicine explore the epidemiology of diabetes and its long-term impact from different perspectives.

04-07-2017 | Continuous glucose monitoring | News

Predictive system reduces hypoglycemia burden in children with type 1 diabetes

Research suggests that a predictive low-glucose management system significantly reduces hypoglycemic events in children and adolescents with type 1 diabetes.

03-30-2017 | Ketoacidosis | News

Acute kidney injury common in pediatric diabetic ketoacidosis

Almost two-thirds of children hospitalized with diabetic ketoacidosis develop acute kidney injury within 24 hours of hospitalization, study findings indicate.

03-01-2017 | Children | News

Type 2 diabetes a complicated problem in children

Type 2 diabetes may carry a higher risk for complications than type 1 diabetes among teenagers and young adults who were diagnosed during childhood or adolescence, shows a US population-based study.

02-21-2017 | Screening | News

Computer decision support prompts pediatric type 2 diabetes investigation

Use of a computer clinical decision support system increases targeted screening of pediatric patients at risk for type 2 diabetes and boosts their attendance at follow-up appointments, shows a randomized trial.

02-10-2017 | Faster-acting insulin aspart | News

Ultrafast-acting insulin effective in children

The pharmacodynamics of faster-acting insulin aspart in children are similar to those in adults, suggesting its ability to improve postprandial glycemic control in children with type 1 diabetes, say researchers.

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