Lifestyle interventions and obesity

The pilot MIDDAS study suggests that a 2-day per week very-low-calorie diet could be a viable alternative to a continuous diet for people with type 2 diabetes who struggle with this approach.

The strongest predictor of type 2 diabetes remission is weight loss, with other variables only modestly associated with outcome and insufficient to identify people unsuitable for attempting this goal, shows a post-hoc analysis of DiRECT data.

Among people with obesity and type 2 diabetes, substantial weight loss is associated with similar metabolic benefits irrespective of whether it is achieved through gastric bypass surgery or diet, suggests research published in The New England Journal of Medicine.

A telehealth-based lifestyle intervention can significantly reduce excessive gestational weight gain relative to usual antenatal care, among pregnant women who are overweight or obese, US study findings indicate.

The results of a small randomized trial suggest exercise is more helpful than diet for combating early cardiac dysfunction associated with type 2 diabetes, although both may be beneficial.

Restricting eating to within a 10-hour daily window results in weight loss and metabolic benefits for people with metabolic syndrome, report researchers in Cell Metabolism.

People who are trying to maintain weight loss with the help of electronic health records-based tracking tools do significantly better if they are given access to an online coach, shows a randomized trial.

Adding intensive weight management to group medical visits for type 2 diabetes leads to greater weight loss, reduced medication use, and fewer hypoglycemic events, with a similar improvement in glycemic control, research shows.

The specific medications people are taking for diabetes can affect their success when they undertake a weight-loss program, say researchers.

Findings from the GRAVITAS trial indicate that use of the GLP-1 receptor agonist liraglutide alongside a diet and physical activity intervention may improve glycemic control among people with persistent or recurrent type 2 diabetes after bariatric surgery.

Obese adults with prediabetes may need a longer-than-recommended course of behavioral weight loss treatment to optimize improvements in glycemic control, US researchers report.

Type 2 diabetes remission can be achieved within 1 year at a cost below the average annual cost of diabetes management, even when including complications, shows an economic evaluation of the DiRECT/Counterweight-Plus weight management program.

Fifteen years of follow-up of the DPP trial shows that although people initially lost more weight with the intensive lifestyle intervention, those assigned to metformin did better at keeping the weight off in the long term.

Following the positive 2-year results of DiRECT, this symposium shared the first-hand experiences of a dietician, a general practitioner, and a person with diabetes who participated in the DiRECT study.

Just over a third of people who undertook a period on a very-low-calorie diet in the DiRECT trial to tackle type 2 diabetes are in remission 24 months later, the investigators have reported.

A behavioral intervention has lasting effects on physical activity levels, fitness, and vascular risk in people with type 2 diabetes, show the 3-year results of the randomized Italian Diabetes and Exercise Study 2.

Less than perfect attendance at commercial weight loss programs does not consign participants to failure, study findings show.

The PREVIEW project investigators have reported broadly positive results, but tempered by issues such as a high dropout rate.

Obese primary care patients referred to a total diet replacement program run by a commercial provider achieve substantial amounts of weight loss a year later, show findings from a randomized trial.

Findings of a randomized trial suggest that challenging people’s habits can lead to sustained weight loss, even if the habits targeted have nothing to do with healthy eating.