Type 2 diabetes risk factors

People with type 1 diabetes have a greater risk for incident cardiovascular and renal disease than those with type 2 diabetes, suggest findings from a French nationwide observational study presented at the virtual 57th EASD Annual Meeting.

The 10-year and lifetime CVD risk of people with type 2 diabetes varies greatly, with the highest risk seen in those with prior CVD, suggests an analysis of data from the CAPTURE study.

The influence metabolic factors have on type 2 diabetes risk falls as people get older, whereas lifestyle factors convey a greater risk with age, show data from a large, prospective cohort in China.

The degree of non-alcoholic fatty liver disease, estimated by fatty liver index, is significantly associated with the risk for progression to type 2 diabetes in people with prediabetes, Spanish study findings indicate.

A large systematic review and meta-analysis has identified racial/ethnic differences in the risk for complications and all-cause mortality among people with diabetes.

UK researchers suggest raising the glycated hemoglobin threshold that is used to identify individuals at high risk for developing type 2 diabetes within 5 years.

Study results suggest that telmisartan use in people with concomitant type 2 diabetes and hypertension is associated with a lower incidence of dementia and ischemic stroke compared with the use of other angiotensin receptor blockers.

Combining 10 weighted polygenic risk scores of variants related to cardiovascular and renal complications in a joint model with traditional risk factors could optimize micro- and macrovascular risk prediction and treatment response in type 2 diabetes, say researchers.

The duration of statin therapy in people with type 2 diabetes may be even more important than the intensity or the achieved level of low-density lipoprotein cholesterol for preventing cardiovascular events, research suggests.

Research from the TODAY2 study suggests that young people with type 2 diabetes, particularly those with poor glycemic control and high blood pressure, experience worsening arterial stiffness and heart rate variability over time.

People with symptoms indicative of diabetic polyneuropathy near the time of type 2 diabetes diagnosis have a “markedly higher” risk for subsequent cardiovascular disease than those without, researchers report.

Genetic ancestry and socioeconomic deprivation are both significantly associated with type 2 diabetes risk, and may interact to modify that risk, study findings indicate.

Among people with type 2 diabetes, those with hypoglycemic events, microvascular complications, or high or unstable glycated hemoglobin levels might have an increased risk for dementia, researchers report.

Implementation of widespread screening for diabetes “radically” alters the cardiovascular risk profile of people with newly detected diabetes, rendering existing cardiovascular risk prediction tools inaccurate, say researchers.

The risk for subclinical atherosclerosis among people at low risk for cardiovascular death increases with increasing glycated hemoglobin levels and is raised even at levels below the prediabetes threshold, research shows.

The onset of dementia in people with type 2 diabetes may be foreshadowed by elevated levels of some vascular risk factors 1 to 2 decades beforehand, say researchers.

People with type 2 diabetes who have trigger finger are likely at an increased risk for cardiovascular disease, say researchers.

People with type 2 diabetes, particularly those diagnosed at a young age, can face an extended wait for medication to treat cardiovascular risk factors, even if they are in a high-risk category, research shows.

The proportion of people with new-onset type 2 diabetes who have high cardiovascular risk has increased consistently over time, with a particularly notable rise in the prevalence of cardiometabolic multimorbidity among young people, researchers report.

People with type 2 diabetes and comorbid rheumatoid arthritis or osteoarthritis have a clinical profile of severe diabetes with poor glycemic control, researchers report.