Type 1 diabetes and glycemic control

Findings from the COVAC-DM study suggest that people with type 1 or type 2 diabetes have an antibody response to COVID-19 vaccination that is similar to healthy individuals, with no association between glycemic control and antibody levels.

Early intensive glycemic control may reduce the long-term risk for foot ulcers in people with type 1 diabetes, suggest data from the Diabetes Control and Complications Trial and Epidemiology of Diabetes Interventions and Complications study.

The proportion of on-target interstitial glucose values falls during the week following initial COVID-19 vaccination in people with type 1 diabetes, study findings indicate.

Keeping meals to their usual daytime slots may help prevent glucose dysregulation in night-shift workers, research shows.

An update from an international study has shown that although glycemic control has improved with time among people with type 1 diabetes, it remains suboptimal and continues to vary substantially by country, age group, and data source.

Findings from the ORACL trial suggest that closed-loop insulin delivery results in better glycemic control than sensor-augmented pump therapy among older adults with longstanding type 1 diabetes.

Risk factors for cardiovascular disease may vary by longitudinal glycated hemoglobin trajectory in people with type 1 diabetes, US researchers report.

Flash glucose monitoring improves glycemic control and reduces diabetic ketoacidosis rates across nearly all age, sex, and sociodemographic strata, regardless of insulin pump use, according to UK observational data.

Findings from the Hypo-RESOLVE study suggest that exposure to hypoglycemia is associated with subsequent negative clinical outcomes in people with diabetes, supporting a key role for hypoglycemia prevention.

Use of diabetes medications and people’s glycemic control were not, overall, adversely affected by the COVID-19 pandemic, despite a reduction in other healthcare measures, say US researchers.

A co-formulation of pramlintide and a prandial insulin offers improved postprandial glucose control and weight loss, without an increased number of injections, show the results of a small crossover trial.

Use of continuous glucose monitoring within the first month of diagnosis is associated with an improvement in glycemic control among youth with type 1 diabetes, indicate findings from the 4T study.

Higher daily glucose variability is associated with greater aortic stiffness irrespective of average glucose levels, indicate findings from The Maastricht Study.

NHANES data indicate that glycemic and blood pressure control in people with diabetes in the USA has deteriorated over recent years, and lipid control has plateaued.

Switching from intermittently scanned to real-time continuous glucose monitoring improves time in range by a clinically relevant percentage, show the findings of the 6-month ALERTT1 trial.

Early findings suggest a novel molecule that selectively targets hepatic glucokinase may improve glucose control and reduce acute complication risk in people with type 1 diabetes.

Elevated glucose levels and glycemic fluctuations during the first week of hospitalization for COVID-19 are associated with an increased risk for unfavorable outcomes, research suggests.

Researchers find that older adults with diabetes are frequently treated to an intensive glycemic target, putting them at risk for poor outcomes, particularly when high-risk agents are used.

Young adults with diabetes type 1 show improvements in clinic attendance rates when a nonmedical transition coordinator is present during the changeover from pediatric to adult diabetes care, say the authors of a Canadian clinical trial.

Better control of blood glucose around the time of conception is associated with better perinatal and maternal outcomes for women with pre-existing diabetes, research shows.