Pediatric type 2 diabetes

Diabetes distress is more common than depression in adolescents with diabetes and is significantly associated with less frequent blood glucose monitoring and higher glycated hemoglobin levels, study findings indicate.

Intensive antidiabetic treatment in adults with newly diagnosed type 2 diabetes slows the decline in beta-cell function, but this is not sustained after the treatment is stopped, show the results of the RISE adult medication study.

The latest analysis from the observational follow-up of the TODAY study participants shows rapid accumulation of cardiovascular risk factors and diabetes complications in people who were diagnosed with type 2 diabetes in youth.

The Ellipse investigators report improved glycemic control at the price of early and mostly mild gastrointestinal events in children and adolescents with type 2 diabetes.

The rate at which BMI changes throughout childhood and adolescence is significantly associated with adult hyperglycemia, independent of BMI level at specific time points, study findings indicate.

The risk for type 2 diabetes in overweight people is higher in those who gained weight after the age of 10 years than in those who were already overweight at that time, researchers report.

The RISE investigators have reported a continued lack of effect of early intensive therapy on beta-cell function decline in children with prediabetes or early type 2 diabetes.

Both excessive and inadequate weight gain during pregnancy are associated with significantly increased cardiometabolic risk factors among the children at age 7 years, researchers from Hong Kong report.

Impaired glucose tolerance in obese youths frequently reverts to normal, although the chances of this happening are strongly influenced by ethnicity, researchers report in The Lancet Child & Adolescent Health.

The RISE trial investigators have found that increased insulin resistance and hyperresponsive beta cells may explain the rapid progression of type 2 diabetes in children.

Only a very small proportion of adolescents and young adults with diabetes who are referred for outpatient psychotherapy actually receive these services, even when there is an integrated pediatric psychologist in the clinic, research shows.

The majority of adolescents and young adults with type 2 diabetes are still being treated with metformin and/or insulin, despite a growing number of medications being available for adults, US study data show.

Children who are overweight only have an increased risk for type 2 diabetes in adulthood if they remain overweight beyond the age of 13 years, according to the results of a large Danish study.

Surgical treatment of severely obese adolescents with type 2 diabetes is associated with better glycemic control and a greater reduction in BMI than medical management, US researchers report.

US researchers call for tailored clinical programs and policies to improve the transition from pediatric to adult care, and thus prevent worsening glycemic control, in young adults with type 2 diabetes.

Session attendance was only moderate and self-monitoring very poor in youths with type 2 diabetes who participated in the TODAY lifestyle programme, an analysis shows.

A study of Danish men suggests that the increased risk for diabetes associated with being overweight in childhood may be reversed if people lose their excess weight by young adulthood.

Two independent studies published in The New England Journal of Medicine explore the epidemiology of diabetes and its long-term impact from different perspectives.

Type 2 diabetes may carry a higher risk for complications than type 1 diabetes among teenagers and young adults who were diagnosed during childhood or adolescence, shows a US population-based study.

Use of a computer clinical decision support system increases targeted screening of pediatric patients at risk for type 2 diabetes and boosts their attendance at follow-up appointments, shows a randomized trial.