Type 1 diabetes and glycemic control

People with type 1 diabetes who take GLP-1 receptor agonists or SGLT2 inhibitors in clinical practice have outcomes that are mostly – but not all – in line with those in controlled trials, say researchers.

Among adolescents with type 1 diabetes, those with better self-care are more likely to have favorable glycated hemoglobin trajectories into early adulthood, study findings suggest.

Delayed prandial insulin boluses are common in people using advanced technologies for the management of type 1 diabetes and are associated with adverse glycemic outcomes, suggest real-world study results.

Researchers find psychologic resilience to be predictive of glycated hemoglobin levels in the 3 years after type 1 diabetes diagnosis.

The improved glycemic control gained from use of intermittently scanned continuous glucose monitoring is sustained for at least 2 years in people with type 1 diabetes, show real-world data.

Gaining the use of a low blood glucose alert by switching from the FreeStyle Libre 1 to 2 reduces the amount of time people with type 1 diabetes spend in hypoglycemia, report researchers.

Use of the MiniMed 780G advanced hybrid closed-loop system leads to greater reductions in glycated hemoglobin levels than conventional treatment in people with poorly controlled type 1 diabetes, ADAPT study data show.

Researchers have found that the early morning psychosocial state of adolescents and young adults with type 1 diabetes explains a proportion of their daily variance in time in range.

Use of the Tandem Control IQ hybrid closed-loop insulin delivery system improves time in range even for users who very rarely bolus for meals or to treat hyperglycemia, an observational study suggests.

People from the lowest socioeconomic strata have a reduced likelihood of improving their glycemic control after attending a type 1 diabetes education course, shows UK research.

Continuous glucose monitoring metrics show early divergence between pregnant women with type 1 diabetes who subsequently give birth to normal weight versus large for gestational age infants, study findings indicate.

Researchers have characterized an atypical form of diabetes in Indian men with low BMI, which has a unique metabolic profile setting it apart from type 1 and type 2 diabetes.

Children and adolescents using an advanced hybrid closed-loop system for type 1 diabetes can tolerate an unannounced snack containing 20 g of carbohydrate without excessive blood sugar fluctuations, Italian researchers report.

Fluctuations in blood glucose levels during the night can adversely impact the psychologic and physical function of people with type 1 diabetes during the following day, report researchers.

Adding daily empagliflozin to closed-loop insulin delivery improves time in range but also increases ketone levels in people with type 1 diabetes, shows a randomized trial.

Italian researchers have compared outcomes of children and adults with type 1 diabetes using Medtronic MiniMed 780G and the Tandem Control IQ closed-loop insulin delivery systems in real-world practice.

Follow-up results from the WISDM trial show that extended use of continuous glucose monitoring leads to reduced hypoglycemia without increasing hyperglycemia risk in older people with type 1 diabetes.

People with type 1 diabetes and poor glycemic control benefit from use of intermittently scanned continuous glucose monitoring versus self-monitored blood glucose, report the Flash UK investigators.

Individuals with type 1 diabetes and residual β-cell function have better nocturnal and postprandial glycemic control than those with no β-cell function, UK study findings indicate.

Patient-controlled diabetes management improves diabetes-related wellbeing and reduces face-to-face visits and non-attendance without negatively impacting glycemic control and other clinical outcomes, Danish researchers report.