Pediatric diabetes glycemic control

Empagliflozin, but not linagliptin, provides “clinically relevant” improvements in glycemic control versus placebo in children and adolescents with type 2 diabetes, report the DINAMO investigators.

Among adolescents with type 1 diabetes, those with better self-care are more likely to have favorable glycated hemoglobin trajectories into early adulthood, study findings suggest.

Researchers have found that the early morning psychosocial state of adolescents and young adults with type 1 diabetes explains a proportion of their daily variance in time in range.

Children and adolescents using an advanced hybrid closed-loop system for type 1 diabetes can tolerate an unannounced snack containing 20 g of carbohydrate without excessive blood sugar fluctuations, Italian researchers report.

Use of continuous glucose monitoring within the first month of diagnosis is associated with an improvement in glycemic control among youth with type 1 diabetes, indicate findings from the 4T study.

Young adults with diabetes type 1 show improvements in clinic attendance rates when a nonmedical transition coordinator is present during the changeover from pediatric to adult diabetes care, say the authors of a Canadian clinical trial.

The use of continuous glucose monitoring does not increase time in range in young children with type 1 diabetes, but may improve other glycemic indices, researchers report.

Children with type 1 diabetes who use the Tandem Control-IQ hybrid closed-loop insulin delivery system spend more time with their blood glucose levels in the target range than those using a sensor-augmented insulin pump, show findings from the iDCL trial.

Glycemic control in youth and young adults with diabetes has not improved with time, and in some cases has worsened, despite more aggressive glycemic targets and increased availability of newer diabetes technology and therapies, shows the SEARCH for Diabetes in Youth Study.

Asymptomatic celiac disease is a frequently occurring comorbidity in people with type 1 diabetes, and transitioning to a gluten-free diet may increase postprandial glycemic variability, researchers report.

People with type 1 diabetes using the Tandem Control-IQ hybrid closed-loop insulin delivery system spent significantly more time within their target blood glucose range than people using a sensor-augmented insulin pump during 6 months of use in the iDCL trial.

Researchers report that women’s educational attainment is strongly associated with the glycated hemoglobin levels of their children with type 1 diabetes.

Factors associated with poor glycemic control in children with type 1 diabetes generally vary according to the insulin regimen used, but family conflict over diabetes management universally impacts all insulin users, US researchers report.

Responsiveness to text message reminders about blood glucose monitoring is associated with glycemic benefit among adolescents with type 1 diabetes, study findings indicate.

Home use of day and night hybrid closed-loop insulin delivery using the Cambridge model predictive control algorithm is feasible in children aged 1–7 years with type 1 diabetes, researchers report.

Just one-fifth of adults, and an even lower proportion of children and adolescents, with type 1 diabetes in the T1D Exchange registry currently meet the ADA target for glycemic control, US researchers report.

The Tandem Basal-IQ predictive low-glucose suspend insulin delivery system significantly reduces the proportion of time adults and children spend in hypoglycemia during 24-hour usage, show findings from the randomized crossover PROLOG trial.

The Flexible Lifestyles Empowering Change intervention has failed to improve glycated hemoglobin levels in a randomized trial involving adolescents with type 1 diabetes, despite improving some psychosocial outcomes.

Continuous subcutaneous insulin infusion therapy significantly lowers glycated hemoglobin levels in young people with type 1 diabetes, but at the cost of an increased risk for diabetic ketoacidosis during the first year, UK researchers report.

A study of type 1 diabetes patients voluntarily following a very-low-carbohydrate diet suggests that the approach could help to achieve excellent control of blood glucose levels.