Pathogenesis

Research shows increased levels of proinsulin in the beta cells of autoantibody-positive people who have not yet developed type 1 diabetes, offering clues to the pathogenic process.

Research suggests that if enteroviruses do indeed contribute to the pathology of type 1 diabetes, then there is a large time lag between infection and the first damaging effects on beta cells.

In: Managing Diabetic Eye Disease in Clinical Practice. Edited by Singh RP. Springer International Publishing, 2015. doi: 10.1007/978-3-319-08329-2_2