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Visceral Fat and Body Composition Changes in a Female Population After RYGBP: a Two-Year Follow-Up by DXA

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Abstract

Background

Our aim was to monitor the impact of Roux-en-Y gastric bypass (RYGBP) on body composition over a 24-month period by dual-energy X-ray absorptiometry (DXA).

Methods

Forty-one women (40.6 ± 10.0 years old; 42.6 ± 6.6 kg/m2) entering a bariatric surgery programme were submitted to whole-body DXA (Lunar iDXA) before treatment and after 3, 6, 12 and 24 months. Fat mass (FM), non-bone lean mass (LM), bone mineral content (BMC) and density (BMD) were measured at whole body and regionally. Android visceral adipose tissue (VAT) was estimated by a recently validated software.

Results

Twenty-nine patients (44.3 ± 11.8 years old; BMI, 45.4 ± 8.9 kg/m2) concluded the study. Following surgery, the progressive decrease of BMI was associated with reduced whole-body and regional FM. LM showed a moderate decrease at 3 months and stabilized thereafter. A progressive decrease of total FM/LM and android FM/LM ratios were observed in the 3- to 6-month (−19.1 ± 8.4 % and −26.5 ± 10.9 %, respectively; p < 0.0001) and 6- to 12-month periods (−23.5 ± 16.8 % and −29.4 ± 23.9 %, respectively; p < 0.0001). VAT was the parameter showing the largest decrease (−65.6 ± 17.5 % at 12 months; p < 0.0001). Two years after the surgery, a slight but significant decrease of total and regional LM was observed, without any significant change in BMI.

Conclusions

Body composition significantly changes after RYGBP with a metabolically healthier redistribution of total and regional FM and a positive balance of FM/LM variation. DXA should be considered as a valid supplementary tool for the clinical assessment and follow-up in patients undergoing bariatric surgery.

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Conflict of Interest

All the authors have no conflict of interest to declare.

Statement of Informed Consent

Informed consent was obtained from all individual participants included in the study.

Statement of Human and Animal Rights

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Authors and Affiliations

  1. Diagnostic and Interventional Radiology, The “Rizzoli” Institute, Via G. C. Pupilli 1, 40136, Bologna, Italy

    Alberto Bazzocchi & Ugo Albisinni

  2. Department of Specialized, Diagnostic, and Experimental Medicine, University of Bologna Sant’Orsola-Malpighi Hospital, Via G. Massarenti 9, 40138, Bologna, Italy

    Federico Ponti, Danila Diano & Giuseppe Battista

  3. Obesity Surgery Center, Department of Emergency-Urgency, General Surgery and Transplantation, University of Bologna Sant’Orsola-Malpighi Hospital, Via G. Massarenti 9, 40138, Bologna, Italy

    Stefano Cariani & Luca Leuratti

  4. Unit of Metabolic Diseases and Clinical Dietetics, University of Bologna Sant’Orsola-Malpighi Hospital, Via G. Massarenti 9, 40138, Bologna, Italy

    Giulio Marchesini

Authors
  1. Alberto Bazzocchi
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  2. Federico Ponti
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  3. Stefano Cariani
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  4. Danila Diano
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  5. Luca Leuratti
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  6. Ugo Albisinni
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  7. Giulio Marchesini
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  8. Giuseppe Battista
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Correspondence to Federico Ponti.

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Bazzocchi, A., Ponti, F., Cariani, S. et al. Visceral Fat and Body Composition Changes in a Female Population After RYGBP: a Two-Year Follow-Up by DXA. OBES SURG 25, 443–451 (2015). https://doi.org/10.1007/s11695-014-1422-8

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  • DOI: https://doi.org/10.1007/s11695-014-1422-8

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