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Intragastric Balloon Insertion Increases the Frequency of Erosive Esophagitis in Obese Patients

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Background

The BioEnterics intragrastric balloon (BIB) has been successfully used for treatment with BMI > 35 or BMI > 40. Gastroesophageal reflux (GER) symptoms are sometimes reported to occur and/or to worsen in patients with BIB, with a variable onset of erosive esophagitis (EE). The aim of this study was to investigate the prevalence and the severity of esophagitis after BIB placement.

Methods

121 patients (93 F, 28 M, mean age 45 (19–65), mean BMI 41.5 (30–63.5) were studied. Patients with severe esophagitis (grade C-D Los Angeles (LA) classification), gastric or duodenal ulcers were excluded from the BIB treatment. After BIB placement, proton-pump inhibitors (PPI) were administered in the first month to each patient. The BIB was removed after 6 months. The presence of EE and related severity by LA classification were recorded.

Results

Before BIB insertion, 18 patients (15%) showed mild EE (16 grade A and 2 grade B). After BIB removal, EE was observed in 22 patients (18.2%): 11 grade A, 7 grade B, 4 grade C-D. The difference in the prevalence of EE after BIB was statistically significant (Wilcoxon’s test P = 0.030).

Conclusion

EE prevalence was significantly increased after BIB placement. We suggest that EE due to enhanced GER could be considered as an adverse effect of such treatment.We therefore recommend maintaining intragastric acid suppression with PPIs during the 6 months of BIB placement.

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Authors and Affiliations

  1. Endoscopia Digestiva, Casa di Cura “Malatesta Novello”, Cesena, Italy

    Angelo Rossi, Gianluca Bersani & Giovanni DeFabritiis

  2. School of Gastroenterology, University of Ferrara, Ferrara, Italy

    Giorgio Ricci, Chiara Petrini & Vittorio Alvisi

  3. Servizio di Endoscopia Digestiva, Casa di Cura Malatesta Novello, Via R. Serra 2, 47023, Cesena (FC), Italy

    Angelo Rossi

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  1. Angelo Rossi
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  2. Gianluca Bersani
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  3. Giorgio Ricci
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  4. Chiara Petrini
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  5. Giovanni DeFabritiis
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  6. Vittorio Alvisi
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Correspondence to Angelo Rossi.

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Rossi, A., Bersani, G., Ricci, G. et al. Intragastric Balloon Insertion Increases the Frequency of Erosive Esophagitis in Obese Patients. OBES SURG 17, 1346–1349 (2007). https://doi.org/10.1007/s11695-007-9239-3

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  • DOI: https://doi.org/10.1007/s11695-007-9239-3

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