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Relationship between healthy lifestyle behaviors and cardiovascular risk factors in Chinese patients with type 2 diabetes mellitus: a subanalysis of the CCMR-3B STUDY

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Abstract

Aims

This subanalysis of a cross-sectional, nationwide study was undertaken to assess the relationship between healthy lifestyle behaviors and multiple cardiovascular risk factors among people with type 2 diabetes mellitus (T2DM).

Methods

Data collected from 25,454 participants, including demographics, lifestyle behaviors and cardiovascular risk profiles, were analyzed. Blood pressure control as well as blood glucose and blood lipid (3Bs) levels were measured as multi-risk factors for cardiovascular disease. Healthy lifestyle behaviors included regular exercise, nonsmoking status and no alcohol consumption. The relationship between the healthy lifestyle behavior(s) and control of 3B(s) was calculated.

Results

Of the 25,454 eligible participants, 4171 (16.4%) were current smokers, 2011 (7.9%) currently consumed alcohol, and 11,174 (43.9%) did not exercise. In total, 654 (2.6%) reported all three unhealthy lifestyle behaviors. Most participants (71.1%) had received at least a high school education and were more likely to smoke and drink as compared to those with lower education. Unhealthy lifestyle behaviors were commonly found in participants with low atherosclerosis risk, such as non-elderly people and those with an above-college education level. Unhealthy lifestyle is associated with poor 3B control and worse medication adherence.

Conclusions

Unhealthy lifestyles are common in Chinese people with T2DM, especially in people who are non-elderly and above-college educated. Interventions aimed at changing risky lifestyle behaviors are required for improved outcomes for Chinese patients with T2DM.

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Acknowledgements

We thank all CCMR-3B STUDY investigators for their contribution to the successful completion of the 3B STUDY.

Funding

This study was supported by an unrestricted grant offered by Merck Sharp & Dohme (China).

Author information

Authors and Affiliations

  1. Department of Endocrinology, Huadong Hospital Affiliated to Fudan University, Shanghai, China

    Yuxin Huang, Jiao Sun, Wen Tan, Suyuan Jiang & Xiaoming Tao

  2. MSD China Holding Co.Ltd., #1582 Gumei Road, Shanghai, 200233, People’s Republic of China

    Jihu Li

  3. Takeda Pharmaceutical China, 1717 East Nanjing road, Shanghai, 200040, People’s Republic of China

    Xiaolin Zhu

  4. Department of Endocrinology and Metabolism, Peking University People’s Hospital, Beijing, China

    Linong Ji

  5. Department of Cardiology, Peking University People’s Hospital, Beijing, China

    Dayi Hu

  6. Department of Endocrinology, Beijing 301 Military General Hospital, Beijing, China

    Changyu Pan

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  1. Yuxin Huang
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on behalf of CCMR-3B STUDY Investigators

Corresponding author

Correspondence to Jiao Sun.

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Conflict of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.

Human and animal rights disclosure

The protocol of this study was approved by the Ethics Committee of Peking University People’s Hospital (Ethics Number: [2010]024). All procedures were performed in accordance with the ethical standards of the institutional research committee and with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.

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Informed consent was obtained from all participants included in this study.

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Huang, Y., Li, J., Zhu, X. et al. Relationship between healthy lifestyle behaviors and cardiovascular risk factors in Chinese patients with type 2 diabetes mellitus: a subanalysis of the CCMR-3B STUDY. Acta Diabetol 54, 569–579 (2017). https://doi.org/10.1007/s00592-017-0981-2

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