Type 2 diabetes in specific populations

Younger age at type 2 diabetes diagnosis is associated with shorter life expectancy, with 3 to 4 years lost for every decade of earlier diagnosis.

Impaired glucose tolerance during pregnancy that does not meet the criteria for gestational diabetes nevertheless increases the likelihood that women will later develop type 2 diabetes, a study shows.

Hypertension has the largest impact on mortality risk in younger people with type 2 diabetes, whereas chronic kidney disease is a greater threat for older people, shows a population-based study.

Empagliflozin, but not linagliptin, provides “clinically relevant” improvements in glycemic control versus placebo in children and adolescents with type 2 diabetes, report the DINAMO investigators.

People with type 2 diabetes who maintain low glycated haemoglobin levels have slower progression of frailty over time than those with higher levels, shows an analysis of Look AHEAD participants.

The incidence and burden of type 2 diabetes in young people aged 15–39 years are increasing worldwide, show data from the Global Burden of Disease Study.

Fully subsidizing continuous glucose monitors could overcome disparities in their use by people with diabetes, suggests research conducted in adults enrolled in a US Medicaid program.

Following a very-low-calorie total diet replacement plan can lead to type 2 diabetes remission in South Asian individuals, shows the STANDby trial.

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People with a South Asian or mixed ethnic background and those with social deprivation have a particularly high risk for progressing from prediabetes to type 2 diabetes, research shows.

Chinese people with new-onset type 2 diabetes have a significantly increased risk for pancreatic cancer relative to the general population, particularly when they are diagnosed at a young age, study findings indicate.

The highest risk for type 2 diabetes occurs in people who progress from a low body size in childhood to a high body size in adulthood, shows an analysis of data from the UK Biobank.

Only two of the five most common comorbidities identified in a UK population with type 2 diabetes are traditionally associated with the condition, say researchers.

The number of people with undiagnosed diabetes in the USA has fallen in the past 3 decades, indicates research published in Diabetes Care.

Diabetes burden is large, heterogenous, and has increased across all six regions of the Americas since 1990, mostly as a result of type 2 diabetes, show data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019.

Deintensifying diabetes treatment does not increase the risk for short-term adverse outcomes in male nursing home residents with limited life expectancy or advanced dementia, say researchers.

Results from the iCount study show that negative beliefs about medicines, unmet material needs, and poor social support are all predictors of low adherence to treatment for individuals with young-onset type 2 diabetes.

The risk for major leg amputation or death after hospitalization for diabetic foot ulcers is elevated in Black people and those living in rural areas, with a 10.4% absolute increase among patients with both risk factors compared with the national rate, US researchers have found.

Researchers recommend using different BMI or age thresholds for type 2 diabetes screening in ethnic minority groups, on finding that a single threshold may miss many cases in non-White Americans.

Less than 10% of people with self-reported diabetes in India meet optimal treatment targets for glycated hemoglobin, blood pressure, and low-density lipoprotein cholesterol control combined, show data from the ICMR-INDIAB study.