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Type 2 diabetes and hypoglycemia

Highlights

emergency_department

08-03-2020 | Hypoglycemia | Highlight | News

Severe hypoglycemia ‘marker rather than cause’ for longer-term type 2 diabetes mortality risk

Severe hypoglycemia in people with type 2 diabetes is associated with later mortality from a wide range of causes, including those for which there is no obvious underlying mechanism, say researchers.

Human kidney cross section on scientific background. 3d illustration

04-16-2020 | Nephropathy | Highlight | News

Hypoglycemia risk with even mild renal dysfunction in real-world practice

A large observational study reveals a strong link between reduced kidney function and increased incidence of hypoglycemia in adults with diabetes in routine clinical practice.

Blood test

10-23-2019 | Hypoglycemia | Highlight | News

Fasting C-peptide indicates hypoglycemia risk at basal insulin initiation

Fasting C-peptide levels can “provide valuable information” to guide the approach to titrating basal insulin in new users with type 2 diabetes, say researchers.

HbA1c

07-12-2019 | Continuous glucose monitoring | Highlight | News

CGM measures have variable correlation with HbA1c

Glycated hemoglobin levels correlate strongly with continuous glucose monitoring-measured average blood glucose and hyperglycemia, but poorly with hypoglycemia, say researchers.

Pills_yellow

01-17-2019 | Glucokinase activators | Highlight | News

Hepatic glucokinase activation may improve glycemic control in type 2 diabetes

The hepatoselective glucokinase activator TTP399 reduces glycated hemoglobin levels without increasing the risk for hypoglycemia among patients with type 2 diabetes, suggest findings from the phase IIb AGATA trial.

AdobeStock_88855376

09-05-2018 | Diagnosis | Case study | Article

Acute illness while on a SGLT2 inhibitor and ketogenic diet

Advisory Board member Theresa Smyth tackles an emergency case in a type 2 diabetes patient treated with empagliflozin. What went wrong and how should he be managed?

Metformin formula

07-18-2018 | Sulfonylureas | Highlight | News

Continuing metformin advisable for patients starting sulfonylurea treatment

Research shows that starting second-line sulfonylurea treatment is associated with an increased risk for cardiovascular and hypoglycemic events among patients with type 2 diabetes in clinical practice, although the risk is less if they continue using metformin rather than switching completely.

Lori Berard

06-06-2018 | Insulin | View from the clinic | Article

Barriers to insulin: Initiation in type 2 diabetes patients

Editorial Board member Lori Berard talks through the stages and challenges associated with preparing type 2 diabetes patients for insulin therapy (9:00).

Stethoscope and map

05-30-2018 | Insulin | Editorial | Article

Hit early, hit hard: The EADSG insulin guidelines

Sanjay Kalra and Silver Bahendeka, East Africa Diabetes Study Group Chair, provide an overview of the latest insulin guidance developed to aid management in a challenging region, facing familiar struggles.

Person holding sweeteners

05-15-2018 | Diet | Article

Glycemic impact of non-nutritive sweeteners: A systematic review and meta-analysis of randomized controlled trials

Nichol AD, Holle MJ, An R. Eur J Clin Nutr 2018. doi: 10.1038/s41430-018-0170-6

Pills

04-03-2018 | Alogliptin | Highlight | News

Support for alogliptin as add-on therapy for type 2 diabetes

Adding the dipeptidyl peptidase-4 inhibitor alogliptin to metformin and sulfonylurea treatment may improve glycemic control in patients with type 2 diabetes and high cardiovascular risk, a post-hoc analysis of the EXAMINE trial suggests.

Doctor having a conversation with a patient

03-28-2018 | Devices and technology | View from the clinic | Article

Managing patient expectations for glucose management via a device

As the utility and availability of devices surges, so too do patient expectations. Advisory Board member Katharine Barnard provides key consultation questions to help determine your patients’ greatest needs and obstacles.

Hospital corridor

03-27-2018 | Inpatient diabetes | Feature | Article

The inpatient diabetes audit: A tool for change

With the 2017 NaDIA results showing some positive trends in inpatient diabetes care, medwireNews talks to national clinical lead Gerry Rayman about the tools and tactics to deliver the best patient outcomes.

Insulin injection (symbolic image with model)

02-23-2018 | Insulin | Practical approach | Article

Insulin matters: A practical approach to basal insulin management in type 2 diabetes

Experts review the evidence and best clinical practices of initiating and titrating insulin in patients with type 2 diabetes and provide guidance and practical recommendations for the healthcare community.

Elderly diabetic patient (symbolic image with models)

02-19-2018 | Older adults | Practical approach | Article

Diabetes in the elderly

This review takes a practical approach to the assessment, nursing care, and medical treatment of diabetes in the elderly, highlighting major challenges and suggesting solutions to common clinical problems.

Pill in hand (symbolic image with model)

02-13-2018 | Older adults | Editorial | Article

Does setting treatment targets risk the overtreatment of type 2 diabetes in older patients?

The drive to achieve lower HbA1c targets in older patients is not without concern or risk. Our UK Board address concerns highlighted by recent trials and discuss whether current guidelines do enough to mitigate the risks of overtreatment.

Case study keyboard

12-13-2017 | Diagnosis | Case study | Article

Atypical diabetes: Case study 3

How would you diagnose and treat the third patient in our series of case studies on atypical forms of diabetes? Editorial board member Jay Shubrook challenges you.

Insulin injection (symbolic image with model)

12-05-2017 | Insulin resistance | Editorial | Article

A pragmatic and practical guide to U500 regular insulin usage

Editorial Board member Sanjay Kalra shares his pragmatic and practical suggestions on initiating, monitoring, and titrating suitable patients on U500 regular insulin.

Insulin pen

11-08-2017 | Long-acting insulins | Editorial | Article

Longer-acting basal insulin analogs: What, how, why, when, and who?

Advisory Board member and pharmacist, Josh Neumiller, presents a practical guide to support clinical decision-making in the initiation and titration of U300 insulin glargine and insulin degludec.