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09-19-2016 | Type 1 diabetes | News | Article

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Hyperglycaemia most frequent issue with artificial pancreas use

medwireNews: A safety study finds that hyperglycaemia is the most common adverse event in patients with Type 1 diabetes using a closed-loop insulin delivery system on an outpatient basis.

During 14 weeks of use, including a 2-week run-in period, there were 28 device-related events among the 124 patients in the study, report Richard Bergenstal (International Diabetes Center, Minneapolis, Minnesota, USA) and colleagues in a research letter in JAMA.

All events were mild and resolved at home. There were no cases of severe hypoglycaemia or ketoacidosis; rather, the most frequent events were hyperglycaemia (six cases) and severe hyperglycaemia (17 cases). Most cases of severe hyperglycaemia (>300 mg/dL) were caused by the infusion set or software or hardware issues.

The patients in this study were aged between 14 and 75 years, but the team notes that a similar study in children is ongoing.

By Eleanor McDermid

medwireNews is an independent medical news service provided by Springer Healthcare Limited. © Springer Healthcare Ltd; 2016

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