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Type 1 diabetes: Complications and comorbidities

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Dual targets difficult to reach in type 1 diabetes

Female archer aiming at target

People with type 1 diabetes treated with multiple daily insulin injections struggle to achieve guideline-recommended targets for time in hypoglycemia while simultaneously reaching their glycated hemoglobin goals, researchers report.

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Variable CGM benefits in high-risk subgroups

CGM

Continuous glucose monitoring is well accepted and reduces time in hypoglycemia among older individuals with type 1 diabetes, report researchers in JAMA.

ADA 2020

Impaired hypoglycemia awareness linked to severe hypoglycemia during pregnancy

Blood sugar check in pregnancy

Impaired awareness of hypoglycemia is associated with an increased risk for severe hypoglycemia and increased fear of hypoglycemia in pregnant women with type 1 diabetes, shows a post-hoc analysis of CONCEPTT data.

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Hybrid insulin regimen may address type 1 diabetes exercise issues

Gym class jumping on boxes

A proof-of-concept study indicates that taking some basal insulin as a single injection of degludec improves glucose control during and after exercise in people with type 1 diabetes who prefer to remove their insulin pump while exercising.

DKA prevalence with newly diagnosed pediatric type 1 diabetes remains high

Motion blur child hospital emergency

A major study of children from three continents suggests that diabetic ketoacidosis remains unacceptably high among those newly identified with type 1 diabetes and shows few signs of improving.

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Hypoglycemia risk with even mild renal dysfunction in real-world practice

Human kidney cross section on scientific background. 3d illustration

A large observational study reveals a strong link between reduced kidney function and increased incidence of hypoglycemia in adults with diabetes in routine clinical practice.

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Islet transplantation benefits endure over 10 years

Islet cells

Three-quarters of people who undergo islet transplantation for type 1 diabetes have sustained graft survival with associated improvements in glucose control, insulin requirements, and hypoglycemia incidence 10 years later, research shows.

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CGM time in range: A higher standard for an engaged few?

CGM_action

Simon Heller explains why time-in-range targets are so helpful for people with diabetes… yet handing out continuous glucose monitoring devices willy-nilly could do more harm than good.

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Protocol with point-of-care testing improves speed, accuracy of DKA diagnosis

Hospital emergency sign

Implementing a nursing protocol that includes point-of-care testing at triage reduces the time to diabetic ketoacidosis diagnosis and the number of unnecessary intravenous placements in the pediatric emergency department, say researchers.

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CGM measures have variable correlation with HbA1c

HbA1c

Glycated hemoglobin levels correlate strongly with continuous glucose monitoring-measured average blood glucose and hyperglycemia, but poorly with hypoglycemia, say researchers.

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01-18-2021 | Hypoglycemia | News

Restored brain functions parallel regain of hypoglycemia awareness

Researchers find partial restoration of brain responses to hypoglycemia in people with type 1 diabetes who recover hypoglycemia awareness during a multifactorial intervention.

01-08-2021 | Ketoacidosis | News

DKA predictors could facilitate targeted SGLT2 inhibitor use in type 1 diabetes

Increased BMI and insulin resistance are important predictors of diabetic ketoacidosis risk among people with type 1 diabetes using SGLT2 inhibitors, say the authors of a meta-analysis and meta-regression.

01-07-2021 | Hypoglycemia | News

Any residual C-peptide offers protection for people with type 1 diabetes

Any amount of residual C-peptide is protective against some type 1 diabetes complications, show findings from a large, population-based study.

Themed collections

06-07-2017 | Psychosocial care | Themed collection | Collection

Psychosocial care in diabetes

This content collection summarizes recent publications dealing with various aspects of psychosocial care in patients with type 1 and type 2 diabetes.

This collection has been developed on behalf of Diabetes UK

Journal articles and book chapters

11-14-2018 | Charcot foot | Article

Varied presentations and outcomes of Charcot neuroarthropathy in patients with diabetes mellitus

Rastogi A, Prakash M, Bhansali A. Int J Diabetes Dev Ctries 2018. doi: 10.1007/s13410-018-0700-8

10-23-2018 | Complications | Article

Validation of time in range as an outcome measure for diabetes clinical trials

Beck RW et al. Diabetes Care 2018: dc181444. doi: 10.2337/dc18-1444

10-08-2018 | Complications | Review | Article

Diabetes and HIV

Noubissi EC, Katte JC, Sobngwi E. Curr Diab Rep 2018; 18: 125. doi: 10.1007/s11892-018-1076-3

09-04-2018 | Mental health | Article

Long-term glycemic control and dementia risk in type 1 diabetes

Lacy ME et al. Diabetes Care 2018: dc180073. doi: 10.2337/dc18-0073

Guidelines

A convenient single access point, providing diabetes professionals with links to a comprehensive set of clinical practice guidelines from a wide range of relevant organizations.

Slides

Downloadable PowerPoint slide sets containing a variety of high-quality images and illustrations from Springer Nature’s library of published figures.

Practice tips

Practical information, guidance, and helpful resources for diabetes healthcare providers. Comprised of practical approaches, case studies, and more.

Themed collections

Compendia of selected, recently published, free full-text journal and book content from Springer Nature and other publishers on a particular topic within diabetes management, as recommended by our Editorial Board.

Independent Medical Education

Educational programs building upon the most current research and professional practice recommendations, with the aim of enabling more efficient diagnosis, optimizing treatment, and improving patient outcomes.

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