Type 1 diabetes and pregnancy

Results of a pilot study show that a hybrid closed-loop insulin delivery system customized for pregnancy used by women with type 1 diabetes at home significantly improved their glucose outcomes.

Pregnant women with type 1 diabetes can achieve similar glucose control regardless of whether they use insulin degludec or detemir, show the results of the randomised EXPECT trial.

Women with type 1 diabetes who have microalbuminuria at the time of pregnancy have an increased risk for adverse pregnancy outcomes in the short term and for diabetes complications in the long term, shows research.

Continuous glucose monitoring metrics show early divergence between pregnant women with type 1 diabetes who subsequently give birth to normal weight versus large for gestational age infants, study findings indicate.

Children born to mothers with autoimmune diseases have an elevated risk for mental disorders, with this risk persisting until early adulthood for those born to women with type 1 diabetes or rheumatoid arthritis, researchers report.

Among pregnant women with preexisting diabetes, those with nephropathy or retinopathy may be at increased risk for pregnancy complications, suggest findings from a systematic review and meta-analysis.

Diabetic ketoacidosis affects around one in 60 pregnant women with type 1 diabetes and is associated with “exceptionally high” perinatal mortality rates, shows research.

The appearance of C-peptide during pregnancy in women with type 1 diabetes and previously undetectable levels may indicate fetal hyperinsulinism and the opportunity to intervene, say researchers.

Integrating a comprehensive management plan into the World Health Organization maternal care framework has the potential to improve pregnancy outcomes for women with type 1 diabetes, suggest findings from the CARNATION study.

Data from the first 5 years of the UK’s National Pregnancy in Diabetes audit reveal differing effects of type 1 and type 2 diabetes on pregnancy outcomes, with no sign of improvements over time.

Better control of blood glucose around the time of conception is associated with better perinatal and maternal outcomes for women with pre-existing diabetes, research shows.

Impaired awareness of hypoglycemia is associated with an increased risk for severe hypoglycemia and increased fear of hypoglycemia in pregnant women with type 1 diabetes, shows a post-hoc analysis of CONCEPTT data.

Children born to mothers with diabetes and severe obesity have an elevated risk for developing neuropsychiatric disorders, researchers report.

People born prematurely may need to be assessed for type 1 and type 2 diabetes early and monitored in the long term, say researchers after finding these individuals may be at increased risk from childhood into adulthood.

Children born to mothers with diabetes have a higher risk for early-onset, non-congenital cardiovascular disease in childhood and early adulthood than those born to mothers without diabetes, suggest findings from a large observational study.

A small Danish study in breastfeeding women with long-term type 1 diabetes could provide useful information on which insulin pump settings to use after childbirth.

A Scottish study has identified glycated hemoglobin levels and BMI as modifiable risk factors for stillbirth among pregnant women with diabetes.

A statement from an ATTD consensus group has streamlined previously agreed continuous glucose monitoring metrics and set out time in range targets.

The risk for preterm birth among women with type 1 diabetes increases considerably with increasing glycated hemoglobin levels around the time of conception, study findings indicate.

Women with gestational diabetes who also have autoantibodies are highly likely to go on and develop type 1 diabetes, research shows.