Skip to main content

Real-world evidence

01-17-2023 | Lifestyle interventions | News

Healthy lifestyle wards off type 2 diabetes microvascular complications

Real-world data from the UK Biobank show the value of a healthy lifestyle in people with type 2 diabetes hoping to avoid microvascular complications.

02-25-2022 | GLP-1 agonists | News

Real-world weight loss with GLP-1 receptor agonists lags behind clinical trials

Only a third of people given a glucagon-like peptide-1 receptor agonist in clinical practice lose a clinically meaningful amount of weight, potentially due to high rates of discontinuation, say researchers.

01-18-2022 | Pregnancy | News

Real-world data support HAPO link between LGA and raised maternal glycemia

Real-world data from Canada show that increasing maternal glycemia is associated with rising rates of large for gestational age births, confirming the results of the landmark HAPO trial.

12-01-2020 | Faster-acting insulin aspart | News

Real-world data support improved glycemic control with faster aspart

Switching to fast-acting insulin aspart significantly improves glycemic control and time in glucose target range in people with type 1 diabetes using continuous glucose monitoring, data from the real-world GoBolus study show.

03-20-2020 | Nephropathy | News

Metformin may be beneficial for people with type 2 diabetes, CKD

Observational study results suggest that metformin use is associated with a reduced risk for mortality and progression to end-stage renal disease, and does not increase the risk for lactic acidosis, among people with type 2 diabetes and chronic kidney disease.

Mature man injecting insulin in his abdomen

01-22-2020 | Insulin glargine | Highlight | News

About 50% attain type 2 glycemic targets with glargine 300 in real-world

Initiating insulin glargine 300 U/mL could help half of those patients whose type 2 diabetes is inadequately controlled with oral antidiabetic medication to achieve their personal glycemic target within a year, real-world data suggest.

03-13-2019 | Canagliflozin | DUKPC 2019 | News

ABCD audit data reveal improved glycemic control with use of FreeStyle Libre, canagliflozin

Analyses of real-world audit data show positive initial results for the flash glucose monitoring system FreeStyle Libre and the sodium-glucose cotransporter 2 inhibitor canagliflozin.

12-07-2018 | Liraglutide (T2DM) | News

Liraglutide cardioprotection replicated in real-world data

Registry data from Denmark and Sweden uphold the cardioprotective effects of liraglutide observed in randomized trials, with the strongest effects seen in patients with established cardiovascular disease.