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Pediatrics

Monoclonal antibody model

10-23-2023 | Type 1 diabetes | News

Teplizumab may PROTECT β-cell function in youth with newly diagnosed type 1 diabetes

Early treatment with the anti-CD3 monoclonal antibody teplizumab may help to preserve β-cell function in children and adolescents with newly diagnosed type 1 diabetes, results of the phase 3 PROTECT study show.

04-05-2023 | Flash glucose monitoring | News

Reduced acute complications for young people using CGM

Data from the DPV cohort show a reduced risk for severe hypoglycemia and diabetic ketoacidosis among children and young people with type 1 diabetes using continuous glucose monitoring rather than self-monitored blood glucose.

03-30-2023 | Artificial pancreas systems | News

Virtual closed-loop initiation success in very young children

The Tandem Control-IQ system delivers improved glucose control versus standard care in children with type 1 diabetes aged between 2 and 6 years and can be initiated virtually, report researchers.

03-21-2023 | Diabetes prevention | News

Verapamil promising for preserving beta-cell function in children

Two linked randomized trials published in JAMA support a role for verapamil, but not for intensive glycemic control, to slow C-peptide decline in children with newly diagnosed type 1 diabetes.

02-03-2023 | Empagliflozin | News

DINAMO: Empagliflozin shows promise for young people with type 2 diabetes

Empagliflozin, but not linagliptin, provides “clinically relevant” improvements in glycemic control versus placebo in children and adolescents with type 2 diabetes, report the DINAMO investigators.

01-26-2023 | Screening | News

Age 10 years is optimal type 1 diabetes screening point for adolescents

“Almost no one” who is islet autoantibody negative at age 10 years despite a high familial risk for type 1 diabetes will develop clinical diabetes by the age of 18, report researchers.

01-09-2023 | Semaglutide | News

FDA approves high-dose semaglutide for adolescents with obesity

Read more about this decision here

12-19-2022 | Early onset | News

Global type 2 diabetes burden increasing in adolescents and young adults

The incidence and burden of type 2 diabetes in young people aged 15–39 years are increasing worldwide, show data from the Global Burden of Disease Study.