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24 search results for:

Maturity-onset diabetes of the young 

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  1. 12-08-2017 | Diagnosis | Case report | Article

    A case of maturity onset diabetes of the young (MODY3) in a family with a novel HNF1A gene mutation in five generations

    Ovsyannikova AK et al. Diabetes Ther 2018; 9: 413. doi: 10.1007/s13300-017-0350-8

  2. 09-22-2022 | EASD 2022 | News | Article

    Support for tailored genetic counseling in people with incidentally discovered MODY mutations

    Mutations in HNF1A and HNF4A are less likely to be associated with a diagnosis of maturity-onset diabetes of the young when discovered incidentally versus in a clinically selected cohort, research suggests.

  3. 06-08-2022 | ADA 2022 | News | Article

    First-in-class glucokinase activator dorzagliatin could help treat some GK-MODY patients

    Dorzagliatin treatment has increased insulin secretion and improved beta-cell function in patients with glucokinase maturity-onset diabetes of the young, also known as MODY2, in a small phase 1 trial.

  4. 06-07-2022 | ADA 2022 | News | Article

    Case series suggests SGLT2 inhibitors could be useful add-on therapy for MODY3

    Results from a small case series in Denmark suggest SGLT2 inhibitors could be a useful add-on therapy for people with maturity-onset diabetes of the young.

  5. 10-27-2022 | Screening | News | Article

    IAA screening may improve classification of autoimmune diabetes in children

    Testing for autoantibodies to endogenous insulin in addition to regular autoantibody screening can increase the proportion of children with an autoimmune classification for newly diagnosed type 1 diabetes, UK research suggests.

  6. 09-23-2022 | EASD 2022 | News | Article

    ​​​​​​​ReTUNE analysis backs ‘personal fat threshold’ concept

    The findings of the ReTUNE study show that losing a substantial amount of weight can reverse type 2 diabetes even in people who are only mildly overweight.

  7. 11-14-2019 | MODY | News | Article

    Islet autoantibody negativity, mild hyperglycemia should trigger MODY genetic screening

    Islet autoantibody negativity plus mild hyperglycemia and a family history of diabetes can be used to identify children newly diagnosed with diabetes who should undergo genetic testing for maturity-onset diabetes of the young, study findings indicate.

  8. 12-17-2021 | Type 1 diabetes | Conference report | Article

    Conference report: ESICON 2021

    Sanjay Kalra reports back from the Golden Jubilee Annual Conference of the Endocrine Society of India.

  9. 09-26-2018 | Monogenic diabetes | News | Article

    Clinical factors predict good glycemic control after MODY treatment switch

    Baseline glucose control, diabetes duration, and BMI all impact whether an individual achieves optimal glucose control after a genetic diagnosis and treatment change for maturity onset diabetes of the young, UK researchers report.

  10. 06-22-2018 | Monogenic diabetes | Review | Article

    Monogenic diabetes in children and adolescents: Recognition and treatment options

    We provide a review of monogenic diabetes in young children and adolescents with a focus on recognition, management, and pharmacological treatment.

  11. 05-18-2018 | Gestational diabetes | Review | Article

    Not quite type 1 or type 2, what now? Review of monogenic, mitochondrial, and syndromic diabetes

    Given the increasing prevalence of diabetes

  12. 12-07-2016 | MODY | News | Article
    News in brief

    Antibody-negative type 1 diabetes may be undiagnosed MODY

    Genetic analysis of children in a national registry reveals undiagnosed maturity-onset diabetes of the young among antibody-negative patients with type 1 diabetes, with implications for their treatment.

  13. 12-08-2016 | Diagnosis | Case report | Article

    What kind of diabetes?

    Owen KR. In: Endocrinology and Diabetes. Edited by Ajjan R, Orme S. Springer, London, 2015. doi: 10.1007/978-1-4471-2789-5_20

  14. 11-01-2017 | Diagnosis | Case study | Article

    Atypical diabetes: Case study 2

    The second case study in our series on atypical forms of diabetes from Jay Shubrook presents a highly distinct variation of the disease and challenges you to make the correct diagnosis.

  15. 12-13-2017 | Diagnosis | Case study | Article

    Atypical diabetes: Case study 3

    How would you diagnose and treat the third patient in our series of case studies on atypical forms of diabetes? Editorial board member Jay Shubrook challenges you.

  16. 09-24-2020 | EASD 2020 | Conference coverage | Article

    GLIMLINA: Glimepiride–linagliptin combination shows potential for HNF1A-MODY

    Adding linagliptin to glimepiride treatment reduces some measures of glycemic variability and improves glycemic control in patients with HNF1A-MODY, indicate findings from the GLIMLINA trial.

  17. 10-29-2019 | Diabetes prevention | Editorial | Article

    The family and diabetes care: A multifaceted relationship

    Before attention turns to World Diabetes Day 2019, Sanjay Kalra revisits 2018’s theme to evaluate the concerns and opportunities presented by “The Family and Diabetes”.

  18. 10-23-2019 | Hypoglycemia | News | Article

    Fasting C-peptide indicates hypoglycemia risk at basal insulin initiation

    Fasting C-peptide levels can “provide valuable information” to guide the approach to titrating basal insulin in new users with type 2 diabetes, say researchers.

  19. 06-08-2019 | Monogenic diabetes | ADA 2019 | Article

    Monogenic diabetes mutations prevalent in type 2 diabetes

    People with type 2 diabetes have a high prevalence of pathogenic mutations in genes typically associated with monogenic diabetes.

  20. 05-22-2019 | Genetics | News | Article

    Exome-wide sequencing study sheds light on type 2 diabetes

    Researchers have used exome-wide sequencing to identify several rare variants within four genes that are significantly associated with type 2 diabetes.

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