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Semin Musculoskelet Radiol 2016; 20(04): 369-375
DOI: 10.1055/s-0036-1592429
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Metabolic Bone Disease in Patients with Malabsorption

Catherine M. Phan
1   Department of Radiology, Saint-Antoine Hospital, Paris, France
,
Giuseppe Guglielmi
2   Department of Radiology, University of Foggia, Foggia, Italy
3   Department of Radiology, Scientific Institute “Casa Sollievo della Sofferenza” Hospital, Foggia, Italy
› Author Affiliations
Further Information

Publication History

Publication Date:
14 November 2016 (online)

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Abstract

Chronic inflammation and malabsorption in gastrointestinal disease can cause bone metabolism alterations and bone mineral loss in children and adults. Gastrointestinal disease is often forgotten as a cause of osteoporosis, osteopenia, or osteomalacia. The etiology of pathologic bone alterations in gastrointestinal disease is multifactorial. Bone alterations were thought to result simply from intestinal malabsorption, but a more complex interaction between cytokines and local/systemic factors influencing bone formation and resorption is envisaged. This review provides an updated discussion on bone alterations in patients with malabsorption due to celiac disease or inflammatory bowel disease.

Keywords

osteoporosis - osteomalacia - bone densitometry - malabsorption - celiac disease/inflammatory bowel disease
 

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