Prediabetes

Testing both glycated hemoglobin and fasting plasma glucose gives a more reliable hyperglycemia diagnosis than either on its own, but a follow-up screening test remains essential, say researchers.

Agreement between five currently recommended definitions of intermediate hyperglycemia, or prediabetes, is poor, and their sensitivity for predicting type 2 diabetes is low, study findings indicate.

A large proportion of people with documented hyperglycemia are still not clinically diagnosed with type 2 diabetes for up to 1 year later, US study data show.

Gujral UP et al. Curr Diab Rep 2018; 18: 60. doi: 10.1007/s11892-018-1017-1

Todd JN, Srinivasan S, Pollin TI. Curr Diab Rep 2018; 18: 57. doi: 10.1007/s11892-018-1025-1

Researchers studying the ARIC cohort have found that virtually all people with elevated fasting plasma glucose and glycated hemoglobin in the same blood sample went on to develop diabetes.

Chen ME, Aguirre RS, Hannon TS. Curr Diab Rep 2018; 18: 51. doi: 10.1007/s11892-018-1023-3

Thankappan KR et al. PLoS Med 2018; 15: e1002575. doi: 10.1371/journal.pmed.1002575

Saetung S et al. Acta Diabetol 2018. doi: 10.1007/s00592-018-1166-3

Vajravelu ME, Lee JM. Curr Diab Rep 2018; 18: 43. doi: 10.1007/s11892-018-1012-6

Juarez LD et al. Diabetes Res Clin Prac 2018. doi: 10.1016/j.diabres.2018.05.009

Song R, Cao S. Diabetes Ther 2018; 9: 1377. doi: 10.1007/s13300-018-0417-1

Research shows that changes in markers of the metabolic syndrome and fatty liver disease are present more than 20 years before people receive a diagnosis of type 2 diabetes.

A blood glucose level taken 1 hour after glucose loading better predicts future type 2 diabetes risk than the level taken at 2 hours, long-term study findings indicate.

Failure to conduct an oral glucose tolerance test results in the underdiagnosis of type 2 diabetes, suggests research.

Jay Shubrook, Chair of the American Diabetes Association’s Primary Care Advisory Group, outlines what's new in 2017's ADA Standards of Care update.