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Pediatric diabetes

Highlights

12-14-2018 | Risk factors | Feature | Article

Sleep duration: Waking up to a major metabolic risk factor

The effect of sleep duration on glucose regulation and cardiometabolic risk is becoming an increasingly high-profile issue. medwireNews takes a look at the latest evidence, which shows the gravity of the problem but also offers some solutions.

10-22-2018 | Mental health | Highlight | News

Insulin manipulation strongly linked to psychiatric comorbidity

Insulin manipulation, the practice of deliberately under- or overdosing insulin, is strongly associated with psychiatric comorbidity in children and young adults with type 1 diabetes, Austrian research shows.

Source:

Pediatr Diabetes 2018; doi:10.1111/pedi.12784

08-10-2018 | Cardiovascular outcomes | Highlight | News

Earlier onset of type 1 diabetes associated with increased risk for adverse outcomes

Patients with type 1 diabetes diagnosed before the age of 10 years have a higher risk for cardiovascular complications and a shorter life expectancy than those who develop the disease at an older age, study results published in The Lancet suggest.

Source:

Lancet 2018; 392: 453–454, 477–486

08-01-2018 | Adolescents | Highlight | News

Motivational interviewing intervention fails to improve HbA1c in adolescents

The Flexible Lifestyles Empowering Change intervention has failed to improve glycated hemoglobin levels in a randomized trial involving adolescents with type 1 diabetes, despite improving some psychosocial outcomes.

Source:

Lancet Child Adolesc Health 2018; doi:10.1016/S2352-4642(18)30208-6


Lancet Child Adolesc Health 2018; doi:10.1016/S2352-4642(18)30241-4

06-26-2018 | Pathophysiology | ADA 2018 | News

RISE: Early insulin does not slow beta cell decline in youth with type 2 diabetes

The RISE trial investigators have found that increased insulin resistance and hyperresponsive beta cells may explain the rapid progression of type 2 diabetes in children.

Source:

Diabetes Care 2018; Advance online publication

06-24-2018 | Pediatrics | ADA 2018 | News

Parents underestimate type 1 diabetes risk in children

Many parents underestimate their child’s risk for type 1 diabetes, and although accuracy improves following a positive autoantibody result, it subsequently declines with time, a survey of TEDDY participants shows.

06-24-2018 | Pathophysiology | ADA 2018 | News

TEDDY data highlight complexities of pediatric diabetes triggers

Researchers speaking at the ADA’s 78th Scientific Sessions in Orlando, Florida, USA, have presented data from The Environmental Determinants of Diabetes in the Young study that begin to shed light on genetic and environmental triggers of pediatric type 1 diabetes.

06-13-2018 | Ketoacidosis | Highlight | News

Fluid management strategy absolved of neurologic injury blame in childhood DKA

Neither the rate of administration nor the sodium chloride content of replacement fluids given to children with diabetic ketoacidosis influences their neurologic outcomes, show the results of the PECARN DKA FLUID Study.

Source:

N Engl J Med 2018; 378: 2275–2287, 2336–2338

06-05-2018 | Neonatal diabetes | Highlight | News

Reassuring long-term data for sulfonylurea in neonatal diabetes

Sulfonylurea treatment is durably effective with a low rate of side effects in patients with permanent neonatal diabetes caused by mutations in the KCNJ11 gene, a study in The Lancet Diabetes & Endocrinology shows.

Source:

Lancet Diabetes Endocrinol 2018; Advance online publication

05-24-2018 | Adolescents | Highlight | News

Insulin, metformin remain most used treatments for type 2 diabetes in youths

The majority of adolescents and young adults with type 2 diabetes are still being treated with metformin and/or insulin, despite a growing number of medications being available for adults, US study data show.

Source:

Pediatr Diabetes 2018; Advance online publication

05-15-2018 | Diet | Article

Glycemic impact of non-nutritive sweeteners: A systematic review and meta-analysis of randomized controlled trials

Nichol AD, Holle MJ, An R. Eur J Clin Nutr 2018. doi: 10.1038/s41430-018-0170-6

05-09-2018 | Diet | Highlight | News

Study suggests benefits of very low carbohydrate intake in type 1 diabetes

A study of type 1 diabetes patients voluntarily following a very-low-carbohydrate diet suggests that the approach could help to achieve excellent control of blood glucose levels.

Source:

Pediatrics 2018; Advance online publication

04-05-2018 | Obesity | Highlight | News

Weight loss before puberty may mitigate excess diabetes risk associated with childhood overweight

Children who are overweight only have an increased risk for type 2 diabetes in adulthood if they remain overweight beyond the age of 13 years, according to the results of a large Danish study.

Source:

N Engl J Med 2018; 378: 1302–1312

03-28-2018 | Devices and technology | View from the clinic | Article

Managing patient expectations for glucose management via a device

As the utility and availability of devices surges, so too do patient expectations. Advisory Board member Katharine Barnard provides key consultation questions to help determine your patients’ greatest needs and obstacles.

Author:
Katharine Barnard

12-14-2017 | Guidelines | Editorial | Article

What is new in the 2018 American Diabetes Association Standards of Medical Care in Diabetes?

Jay Shubrook, Chair of the American Diabetes Association’s Primary Care Advisory Group, outlines what's new in 2018's ADA Standards of Care update. 

Author:
Jay Shubrook

10-07-2017 | Neonatal diabetes | Case report | Article

Neonatal diabetes in a patient with IPEX syndrome: An attempt at balancing insulin therapy

Romano F et al. Acta Diabetol 2017; 54: 1139. doi: 10.1007/s00592-017-1057-z

07-30-2016 | Psychosocial care | Article

Physical activity in youth with type 1 diabetes: A review

Tully C et al. Curr Diab Rep 2016; 16: 85. doi: 10.1007/s11892-016-0779-6

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