Pediatric diabetes and insulin treatment

Starting children on an insulin pump within 6 months of type 1 diabetes diagnosis is associated with improved outcomes relative to delaying for 2 or 3 years, shows an analysis of data from the DPV registry.

Factors associated with poor glycemic control in children with type 1 diabetes generally vary according to the insulin regimen used, but family conflict over diabetes management universally impacts all insulin users, US researchers report.

This 15-minute case presents the identification of problematic hypoglycemia and the appropriate use and monitoring of different technologies in the context of reducing the occurrence and risk of hypoglycemia.

Get more on: Hypoglycemia | Devices and technology | Pediatric diabetes

Insulin manipulation, the practice of deliberately under- or overdosing insulin, is strongly associated with psychiatric comorbidity in children and young adults with type 1 diabetes, Austrian research shows.

The RISE trial investigators have found that increased insulin resistance and hyperresponsive beta cells may explain the rapid progression of type 2 diabetes in children.

The majority of adolescents and young adults with type 2 diabetes are still being treated with metformin and/or insulin, despite a growing number of medications being available for adults, US study data show.

A systematic review and meta-analysis of randomized controlled trials was conducted to quantitatively synthesize existing scientific evidence on the glycemic impact of non-nutritive sweeteners [read more].
Nichol AD, Holle MJ, An R. Eur J Clin Nutr 2018. doi: 10.1038/s41430-018-0170-6

Get more on: Type 2 diabetes | Glycemic control | Diet and nutritional management

As the utility and availability of devices surges, so too do patient expectations. Advisory Board member Katharine Barnard provides key consultation questions to help determine your patients’ greatest needs and obstacles [read more].

Get more on: Devices and technology | Psychosocial care | Type 1 diabetes | Type 2 diabetes

The authors describe the case of a male newborn with persistent hyperglycemia a few hours following birth and suspected immune dysregulation, polyendocrinopathy, enteropathy and X-linked (IPEX) syndrome [read more].
Romano F et al. Acta Diabetol 2017; 54: 1139. doi: 10.1007/s00592-017-1057-z

Get more on: Monogenic diabetes | Neonatal diabetes | Pediatric hyperglycemia