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Obesity: Diet and nutritional management

medwireNews

05-04-2023 | Diet | News

DiRECT extension shows potential for persistent type 2 diabetes remission

The 5-year DiRECT results show sustained type 2 diabetes remission for 13% of the intervention group.

04-25-2023 | Diet | News

Time-restricted fasting improves postprandial glucose tolerance

Restricting fast-day eating to the morning has a positive effect on postprandial glucose versus standard calorie restriction among people at increased risk for type 2 diabetes who are trying to lose weight, a study shows.

Tape measure - overweight obesity concept

02-14-2023 | Obesity | News

Obesity as prevalent in type 1 diabetes as general US population

There is a “substantial” burden of overweight and obesity among people with type 1 diabetes, say US researchers who found rates to be in line with that of the general population.

12-16-2022 | Diet | News

Intermittent fasting feasible with insulin-treated type 2 diabetes

A randomized trial reveals benefits of intermittent fasting, without an increased risk for severe hypoglycemia, in people with insulin-treated type 2 diabetes.

12-13-2022 | Diet | News

Low-carb, high-fat diet gives glycemic benefits in randomized trial

Randomized trial findings show reduced glycated hemoglobin and bodyweight in people with type 2 diabetes following a calorie-unrestricted low-carbohydrate, high-fat diet versus a high-carbohydrate, low-fat approach.

09-23-2022 | EASD 2022 | Conference coverage | News

​​​​​​​ReTUNE analysis backs ‘personal fat threshold’ concept

The findings of the ReTUNE study show that losing a substantial amount of weight can reverse type 2 diabetes even in people who are only mildly overweight.

04-21-2022 | Diet | News

Time-restricted eating benefits may rely on calorie reduction

A randomized trial in The New England Journal of Medicine shows no benefit of adding time-restricted eating to 12 months of calorie reduction in people with obesity.

10-12-2021 | Diet | News

DiRECT insights highlight ‘ongoing struggle’ of maintaining weight loss

Many participants of DiRECT found reintroduction of food and subsequent weight-loss maintenance to be more challenging than the 800 calorie total meal replacement phase, the investigators report.

09-29-2021 | EASD 2021 | Conference coverage | News

Intra-organ fat reduction parallels type 2 diabetes remission in lean people

Outwardly lean people who have type 2 diabetes have increased intra-organ fat, reductions in which occur in line with weight loss-induced diabetes remission, say researchers.

07-09-2021 | Obesity | News

Brain MRI offers clues to weight regain after surgery vs diet

Divergent changes in brain activity after bariatric surgery versus a very-low-calorie diet may help explain why people are more likely to regain weight after the latter intervention, a study suggests.

05-31-2021 | Hypertension | News

DiRECT analysis supports antihypertensive withdrawal before very-low-calorie diet

Blood pressure falls markedly when people with type 2 diabetes undertake a very-low-calorie diet, and immediate withdrawal of antihypertensive medications has few ill effects, say the DiRECT investigators.

05-05-2021 | Liraglutide (obesity) | News

Liraglutide beneficial for post-diet weight loss maintenance

A randomized trial supports giving people with obesity liraglutide to maintain weight loss after an 8-week diet, particularly if it is combined with regular vigorous exercise.

04-29-2021 | DUKPC 2021 | Conference coverage | News

Liver, pancreatic fat may underlie ‘disproportionately raised’ CV risk in women with diabetes

Women naturally have lower levels of hepatic and pancreatic fat than men, but having type 2 diabetes removes this advantage and confers a relatively larger increase in cardiovascular risk, show further data from DiRECT.

Low-carb diet

01-20-2021 | Diet | News

‘Moderate to low’ quality evidence for diabetes remission with low-carb diets

A systematic review and meta-analysis highlights a potential increase in the likelihood of achieving type 2 diabetes remission on a low- or very-low-carbohydrate diet, but based on evidence of moderate or low quality.

Weight gain

01-12-2021 | Diet | News

Ghrelin changes predict weight regain after DiRECT diet

Ghrelin is the only appetite-related hormone that predicted weight regain among the participants of the DiRECT trial, say the researchers.

10-09-2020 | Diet | News

Pancreatic morphology normalizes with sustained type 2 diabetes remission

Sustained remission of type 2 diabetes in DiRECT was accompanied by normalization of pancreatic morphology, say the researchers.

Man checking body fat (symbolic image with model)

09-25-2020 | EASD 2020 | Conference coverage | News

Intermittent very-low-calorie diet could be easier to stomach for people with diabetes

The pilot MIDDAS study suggests that a 2-day per week very-low-calorie diet could be a viable alternative to a continuous diet for people with type 2 diabetes who struggle with this approach.

09-09-2020 | Diet | News

Weight loss strongest predictor of remission in DiRECT

The strongest predictor of type 2 diabetes remission is weight loss, with other variables only modestly associated with outcome and insufficient to identify people unsuitable for attempting this goal, shows a post-hoc analysis of DiRECT data.

Bariatric surgery

08-19-2020 | Metabolic surgery | News

‘Nearly identical’ metabolic benefits with surgery vs diet in people with type 2 diabetes

Among people with obesity and type 2 diabetes, substantial weight loss is associated with similar metabolic benefits irrespective of whether it is achieved through gastric bypass surgery or diet, suggests research published in The New England Journal of Medicine.

Older couple exercising in the park

04-06-2020 | Heart failure | Highlight | News

Exercise better than diet to combat early heart changes in type 2 diabetes

The results of a small randomized trial suggest exercise is more helpful than diet for combating early cardiac dysfunction associated with type 2 diabetes, although both may be beneficial.