Elsevier

Value in Health

Volume 10, Issue 1, January–February 2007, Pages 3-12
Value in Health

A Checklist for Medication Compliance and Persistence Studies Using Retrospective Databases

https://doi.org/10.1111/j.1524-4733.2006.00139.xGet rights and content
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Abstract

The increasing number of retrospective database studies related to medication compliance and persistence (C&P), and the inherent variability within each, has created a need for improvement in the quality and consistency of medication C&P research. This article stems from the International Society of Pharmacoeconomics and Outcomes Research (ISPOR) efforts to develop a checklist of items that should be either included, or at least considered, when a retrospective database analysis of medication compliance or persistence is undertaken. This consensus document outlines a systematic approach to designing or reviewing retrospective database studies of medication C&P. Included in this article are discussions on data sources, measures of C&P, results reporting, and even conflict of interests. If followed, this checklist should improve the consistency and quality of C&P analyses, which in turn will help providers and payers understand the impact of C&P on health outcomes.

Keywords

compliance
guidelines
persistence
retrospective databases

Cited by (0)

Writing for the Analytic Methods Working Group, Medication Compliance and Persistence Special Interest Group, and International Society of Pharmacoeconomics and Outcomes Research (ISPOR).

Analytic Methods Working Group: Josh Benner, PharmD, ScD, Joyce A. Cramer, BS, Femida Gwadry-Sridhar, PhD, David Nau, PhD, Michael Nichol, PhD, Andrew M. Peterson, PharmD, Saurabh Ray, PhD, and Anuja Roy, MBA, MSc.