Lifestyle interventions and cardiovascular disease

People with impaired glucose tolerance who received metformin or intensive lifestyle intervention during the DPP trial show no sign of a significantly reduced cardiovascular disease risk 21 years later, reveal the latest DPPOS results.

Following a low glycemic index or glycemic load diet in addition to standard treatment is associated with improvements in glycemic control and other cardiometabolic risk factors in people with diabetes, suggest the results of a systematic review and meta-analysis.

Blood pressure falls markedly when people with type 2 diabetes undertake a very-low-calorie diet, and immediate withdrawal of antihypertensive medications has few ill effects, say the DiRECT investigators.

People with type 2 diabetes have around a fourfold increased risk for heart disease relative to those without, but having a healthy lifestyle may lessen this risk, researchers report.

The risk for heart failure falls significantly with reductions in fat mass and waist circumference in overweight or obese people with type 2 diabetes, shows an analysis of data from the Look AHEAD trial.

Among the latest findings from the DPP Outcomes Study is that long-term use of metformin does not affect the risk for cancer.

Glucose-lowering drugs or strategies reduce the risk for major adverse cardiovascular events and death in people with or at risk for type 2 diabetes, but their impact on heart failure may depend on weight loss, shows an updated systematic review and meta-analysis.

The results of a small randomized trial suggest exercise is more helpful than diet for combating early cardiac dysfunction associated with type 2 diabetes, although both may be beneficial.

Regularly counseling patients with diabetes about their lifestyles during routine care could benefit their long-term clinical outcomes, US research suggests, possibly due to improved blood glucose control.

Delaying diabetes onset by at least 6 years in people with impaired glucose tolerance significantly reduces their risk for cardiovascular disease and microvascular complications, show 30-year data from the Da Qing Diabetes Prevention Study.

Lifestyle interventions to delay the onset of type 2 diabetes result in marked long-term reductions in cardiovascular disease and mortality, shows the 30-year follow-up of the Da Qing Diabetes Prevention Outcome Study.

A 1-year exercise intervention combining high-intensity interval training with resistance training may improve measures of cardiovascular risk among people with type 2 diabetes, suggests a secondary analysis of the D2FIT trial.

A healthy lifestyle bestows the same degree of relative risk reduction for type 2 diabetes irrespective of whether people have high or low genetic risk for the condition, shows an analysis of UK Biobank data.

A 6-year diet and exercise intervention significantly reduces the long-term risk for cardiovascular disease in Chinese adults with impaired glucose tolerance, research suggests.

Following a healthy lifestyle halves the risk for developing cardiovascular disease in adults with type 2 diabetes, research shows.

The PURE study shows that the cardiovascular disease and mortality risk reductions attainable with regular physical activity apply regardless of whether people live in countries with high, middle, or low income.

Researchers presented the results of several studies investigating the risks associated with nonalcoholic fatty liver disease and potential treatment strategies at the EASD annual meeting in Lisbon, Portugal.

A study has found that a pragmatic lifestyle modification program can significantly reduce predictors of cardiometabolic disease in a young, urban, at-risk South Asian population.

Two analyses of the Prospective Urban Rural Epidemiology cohort associate low dietary fat and high carbohydrate intake with an atherogenic lipid profile and increased mortality.

A machine-learning analysis suggests the existence of heterogeneous treatment effects in the Look AHEAD trial, which could account for the overall neutral effect of the study intervention on cardiovascular outcomes.