Sex difference in HF diabetes impact extended to Asians
medwireNews: Registry data support a larger impact of diabetes on hospitalization and mortality risk in women than men with heart failure (HF).
Most previous research originated from Western countries and is relatively old, however, and the researchers behind this latest study, which draws data from the KorHF registry, say their findings extend the association to Asian people receiving the latest HF treatments.
As reported in Diabetic Medicine, Myung-A Kim (Seoul National University College of Medicine, South Korea) and team assessed data from 3162 people with HF, 30.8% of whom had diabetes, along with a more unfavorable cardiovascular risk profile than people without diabetes.
They found that people who had diabetes were more likely to be admitted to hospital or to die of any cause than those who did not, but this was significant only in women, with rates of 49.7% and 45.0%, respectively, giving a 43.0% risk increase after accounting for confounders. The corresponding rates in men were 46.6% and 41.7%, and the difference remained nonsignificant after multivariate adjustment.
“Customized approaches to individual prognostic factors are very important for avoiding poor prognosis of the heart failure,” say the researchers, stressing that “careful and strict management strategies” are particularly critical in women with diabetes and HF.
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