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Heart failure and diabetes mellitus


Epidemiology

High prevalence of previously unknown heart failure and left ventricular dysfunction in patients with type 2 diabetes

This cross-sectional study assessed the prevalence of previously unknown heart failure and left ventricular dysfunction in elderly patients with type 2 diabetes.

Summary points
  • Patient population consisted of 581 individuals with type 2 diabetes, who did not have a diagnosis of heart failure confirmed by a cardiologist. Mean age was 71.6 years and 53.4% were male.
  • Previously unknown heart failure was diagnosed in 161 patients (27.7%).
  • Of these, 28 patients (4.8%) had reduced ejection fraction, while 133 patients (22.9%) had preserved ejection fraction.
  • The prevalence of heart failure increased with age and was higher in female than in male patients (31.0% vs 24.8%).
  • The prevalence of heart failure was higher in patients with BMI ≥30 kg/m2, dyspnea, fatigue and in those treated for hypertension (compared with patients who did not have these conditions).
  • Left ventricular dysfunction was found in 150 (25.8%) patients, with diastolic dysfunction accounting for the majority (146 patients, 25.1%) of cases.
  • Causes of heart failure were multi-factorial; the most common likely causes of heart failure were hypertension (82.0%), other ischemic heart disease (39.8%), diabetic cardiomyopathy (29.8%), valvular disease (23.6%) and prior myocardial infarction (23.0%).
  • Screening for heart failure should be considered in patients with type 2 diabetes.

Boonman-de Winter LJ et al. Diabetologia 2012; 55: 2154–2162. doi: 10.1007/s00125-012-2579-0

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