Type 2 diabetes

The use of esmolol hydrochloride in adults with diabetic foot ulcer improves wound healing and may constitute a novel treatment option, suggests research reported at the 58th EASD Annual Meeting in Stockholm, Sweden.

YouTube videos about diabetic foot examination are popular, but of poor quality, report UK researchers.

People with diabetes who attend an annual wellness check are significantly less likely to require a major lower extremity amputation within the same year, shows research from the US Diabetes Belt.

The risk for major leg amputation or death after hospitalization for diabetic foot ulcers is elevated in Black people and those living in rural areas, with a 10.4% absolute increase among patients with both risk factors compared with the national rate, US researchers have found.

A prospective analysis of the community-based ARIC cohort supports an increased serious infection risk for people with diabetes.

Negative pressure wound therapy does not improve the closure of chronic diabetic foot wounds compared with current standard treatment in German real-life clinical practice, multicenter trial findings suggest.

People with diabetes have a higher incidence of lower extremity amputation than those without, and individuals with type 1 diabetes have a particularly high risk, research suggests.

Home use of cyclical pressurized topical wound oxygen therapy in addition to standard care increases the likelihood of diabetic foot ulcers completely healing more than fourfold, a sham-controlled trial indicates.

A low-cost, smartphone-based infrared (IR) camera works as well as a high-end version for the detection of diabetic foot ulcers (DFU), study findings indicate.

How many real-world studies have looked at amputation risk in users of SGLT2 inhibitors, and do the findings support or refute the effect found in CANVAS? medwireNews rounds up the research so far.

Rastogi A, Prakash M, Bhansali A. Int J Diabetes Dev Ctries 2018. doi: 10.1007/s13410-018-0700-8

Using smart insoles that alert patients to areas of high pressure can markedly reduce their risk for developing diabetic foot ulcers, show the findings of a randomized trial.

Weekly application of an autologous immune cell, fibrin, and platelet patch significantly increases the rate of healing of hard-to-heal foot ulcers compared with standard care in people with diabetes, randomized trial data show.

Patients with diabetes who are at high risk for foot ulceration are more likely to die than to require amputation, report researchers.

Patients who receive more than 3 weeks of antibiotic treatment for diabetic foot infection are no less likely to develop further infection than those treated for a shorter duration, study findings indicate.

Uazman Alam and colleagues interrogate current evidence and real-world clinical scenarios to address whether enough is being done with the tools available to screen and diagnose diabetic neuropathy.

Dhatariya K et al. Diabetes Care 2018: dc181094. doi: 10.2337/dc18-1094

Wilding J et al. Diabetes Ther 2018. doi: 10.1007/s13300-018-0471-8

Vibha SP et al. BMC Endocr Disord 2018; 18: 43. doi: 10.1186/s12902-018-0270-2

Maskarinec G et al. Eur J Clin Nutr 2018. doi: 10.1038/s41430-018-0188-9