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Sulfonylureas

Expert opinion editorial

The CAROLINA trial: Make or break for sulfonylureas?

Diabetologist Sanjay Kalra puts the CAROLINA trial into historical context and considers the present-day implications for the use of DPP-4 inhibitors and sulfonylureas. 

Get more on: Sulfonylureas | DPP-4 inhibitors | Other diabetes medications

medwireNews editor's pick

Poor availability, affordability compromise global diabetes medication use

Diabetes medications are frequently unavailable and unaffordable, particularly in lower-income countries, shows an analysis of the PURE study.

medwireNews editor's pick

Continuing metformin advisable for patients starting sulfonylurea treatment

Research shows that starting second-line sulfonylurea treatment is associated with an increased risk for cardiovascular and hypoglycemic events among patients with type 2 diabetes in clinical practice, although the risk is less if they continue using metformin rather than switching completely.

medwireNews editor's pick

Reassuring long-term data for sulfonylurea in neonatal diabetes

Sulfonylurea treatment is durably effective with a low rate of side effects in patients with permanent neonatal diabetes caused by mutations in the KCNJ11 gene, a study in The Lancet Diabetes & Endocrinology shows.

medwireNews editor's pick

Glyburide ‘not justified’ as first-line gestational diabetes treatment

A head-to-head trial in women with gestational diabetes has failed to prove that glyburide is statistically noninferior to insulin in terms of perinatal outcomes.

Journal article

Clinical management of women with monogenic diabetes during pregnancy

Here, we will review the pathophysiology of the common forms of monogenic diabetes and recent evidence and recommendations for management during pregnancy [Read more].
Dickens LT, Naylor RN. Curr Diab Rep 2018; 18: 12. doi: 10.1007/s11892-018-0982-8

Get more on: Monogenic diabetes | Diabetes in pregnancySulfonylureas 

Expert opinion editorial

Does setting treatment targets risk the overtreatment of type 2 diabetes in older patients?

The drive to achieve lower HbA1c targets in older patients is not without concern or risk. Our UK Board address concerns highlighted by recent trials and discuss whether current guidelines do enough to mitigate the risks of overtreatment [read more].

Get more on: Medication | Older adults |  Type 2 diabetes

medwireNews

31-08-2023 | Type 2 diabetes | News

Pragmatic trial suggests best cardioprotective agents for type 2 diabetes

SGLT2 inhibitors and GLP-1 receptor agonists appear to offer the best protection against major adverse cardiovascular events in people with type 2 diabetes.

24-04-2023 | Sulfonylureas | News

Sulfonylureas ‘unlikely’ to increase CV, mortality risk in real-world use

Findings from a Scottish national cohort study show that the use of sulfonylureas as second-line glucose-lowering therapy is not associated with elevated cardiovascular risk or all-cause mortality.

14-10-2022 | Dementia | News

Glitazone use linked to reduced dementia risk in type 2 diabetes

People aged 60 years or older receiving thiazolidinedione monotherapy for type 2 diabetes may have a lower risk for dementia than those taking metformin monotherapy, an observational study suggests.

Themed collections

New Content Item

22-05-2017 | Heart failure | Themed collection | Collection

Heart failure and diabetes mellitus

This collection provides an overview of the epidemiology, underlying pathophysiological mechanisms, screening, assessment and management of heart failure in patients with diabetes mellitus.

Journal articles and book chapters

22-06-2018 | Monogenic diabetes | Review | Article

Advances in the genetics of youth-onset type 2 diabetes

Todd JN, Srinivasan S, Pollin TI. Curr Diab Rep 2018; 18: 57. doi: 10.1007/s11892-018-1025-1

Guidelines

Guidelines

A convenient single access point, providing diabetes professionals with links to a comprehensive set of clinical practice guidelines from a wide range of relevant organizations.

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Downloadable PowerPoint slide sets containing a variety of high-quality images and illustrations from Springer Nature’s library of published figures.

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Themed collections

Themed collections

Compendia of selected, recently published, free full-text journal and book content from Springer Nature and other publishers on a particular topic within diabetes management, as recommended by our Editorial Board.

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