medwireNews: Researchers find that a single questionnaire item assessing vitality predicts major adverse cardiovascular events (MACE) in people with type 2 diabetes.
As reported in Diabetic Medicine, Hanna Israelsson (Linköping University, Sweden) and study co-authors found that only the item “seldom having a lot of energy” remained significantly associated with the risk for MACE when they included all studied items from the SF-36 quality of life questionnaire in the same model.
They initially looked at the four items in the vitality domain and the five in the emotional wellbeing domain individually, finding that three from the former and one from the latter domain were associated with MACE after accounting for factors including age, sex, diabetes duration, glycated hemoglobin, and blood pressure.
Negative responses to these items were associated with an approximately 20–30% increased risk for MACE among the 756 people with type 2 diabetes who participated in the study. During a median follow-up of 11.6 years, 16% of these people had MACE.
“We suggest that this question may be included in future risk algorithms in clinical practice for cardiovascular risk stratification in patients with [type 2 diabetes] as an easy way to get additional prognostic information about the risk of cardiovascular disease and death,” conclude the researchers.
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Diabet Med 2022; doi:10.1111/dme.14938