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Prediabetes and prevention

Specific populations

21-03-2023 | Diabetes prevention | News

Verapamil promising for preserving beta-cell function in children

Two linked randomized trials published in JAMA support a role for verapamil, but not for intensive glycemic control, to slow C-peptide decline in children with newly diagnosed type 1 diabetes.

18-11-2022 | Teplizumab | News

FDA clearance for teplizumab to slow type 1 diabetes onset

Click through to read more on this announcement

11-11-2022 | Prediabetes | News

Ethnicity, deprivation increase risk for prediabetes progression

People with a South Asian or mixed ethnic background and those with social deprivation have a particularly high risk for progressing from prediabetes to type 2 diabetes, research shows.

09-05-2022 | Screening | News

Ethnic-specific cutoffs proposed for type 2 diabetes screening

Researchers recommend using different BMI or age thresholds for type 2 diabetes screening in ethnic minority groups, on finding that a single threshold may miss many cases in non-White Americans.

16-04-2021 | Pathophysiology | News

Familial, sporadic type 1 diabetes are ‘overall similar’

Children with familial type 1 diabetes have different characteristics to those with sporadic diabetes at presentation, but longer-term outcomes are similar, say researchers.

09-02-2021 | Older adults | News

Prediabetes a poor predictor of outcomes in older adults

Adults who develop prediabetes when older than 70 years are more likely to regress to normoglycemia or die of other causes than to progress to type 2 diabetes, research shows.

Women with headscarfs sitting in Barcelona city

02-07-2020 | Prediabetes | Highlight | News

Neighborhood walkability may reduce ethnic disparities in diabetes risk

The increased risk for prediabetes among ethnic minorities compared with White people is less pronounced in neighborhoods with high walkability, shows a Canadian study.

01-04-2020 | Liraglutide (obesity) | News

Liraglutide for weight loss successful in obese adolescents

Liraglutide 3.0 mg boosts weight loss in obese adolescents receiving lifestyle therapy, show the findings of a phase 3 trial.

02-01-2020 | Ethnic groups | News

Insulin resistance may be critical type 2 diabetes driver in Chinese people

Insulin resistance may be a more important determinant of type 2 diabetes risk in Chinese people than impaired beta-cell function, show findings from a large population-based study.

04-12-2019 | Adolescents | News

NHANES uncovers scale of prediabetes problem in US youth

A US survey suggests nearly one in five adolescents and one in four young adults has prediabetes and that the condition is linked to an unfavorable cardiometabolic risk profile.

02-12-2019 | Pathophysiology | News

Type 1 diabetes risk ‘varies substantially’ in autoantibody-positive individuals

Among individuals with multiple autoantibodies detected by screening, type 1 diabetes risk varies according to age, autoantibody type, and metabolic impairment, researchers report.

Doctor checking blood sugar of senior patient

29-11-2019 | Older adults | Highlight | News

Prediabetes not an immediate mortality concern in older adults

Prediabetes has no effect on the short-term mortality risk of older adults, suggests an analysis of the Atherosclerosis Risk in Communities study.

24-09-2019 | Type 2 diabetes | Podcast | Article

How was it for you? The experts discuss EASD 2019

Our clinical advisors discuss their EASD 2019 highlights, including new treatment options for children and older adults with type 2 diabetes, the complexities surrounding hypoglycemia prevention, and the implications of the VERIFY trial.

01-07-2019 | Ethnic groups | News

Lifestyle interventions reduce diabetes risk in South Asians

Meta-analysis data show that lifestyle modification interventions can reduce the risk for developing type 2 diabetes by more than a third in high-risk adults of South Asian origin.

John Wilding

13-06-2019 | Prediabetes | ADA 2019 | Article

Expert commentary: The RISE study

With all three RISE studies now published, John Wilding reflects on the pathophysiological differences between children and adults with type 2 diabetes (2:12).

10-06-2019 | Prediabetes | ADA 2019 | News

RISE adult medication results highlight disparity with youth with diabetes

Intensive antidiabetic treatment in adults with newly diagnosed type 2 diabetes slows the decline in beta-cell function, but this is not sustained after the treatment is stopped, show the results of the RISE adult medication study.

24-10-2018 | Obesity | News

BMI trajectory linked to hyperglycemia risk irrespective of BMI level

The rate at which BMI changes throughout childhood and adolescence is significantly associated with adult hyperglycemia, independent of BMI level at specific time points, study findings indicate.

09-10-2018 | Children | EASD 2018 | News

RISE pediatric findings consistent over longer term

The RISE investigators have reported a continued lack of effect of early intensive therapy on beta-cell function decline in children with prediabetes or early type 2 diabetes.

Pregnancy and glucose test

12-09-2018 | Gestational diabetes | Highlight | News

IADPSG gestational diabetes criteria predict later dysglycemia

Less stringent criteria for gestational diabetes remain predictive of risk for later prediabetes or type 2 diabetes despite identifying a larger number of women, the HAPO FUS investigators report in JAMA.

29-08-2018 | Risk factors | Review | Article

Early-life exposures and risk of diabetes mellitus and obesity

Gingras V, Hivert MF, Oken E. Curr Diab Rep 2018; 18: 89. doi: 10.1007/s11892-018-1050-0