Pediatric type 1 diabetes

Continuous glucose monitoring is well accepted and reduces time in hypoglycemia among older individuals with type 1 diabetes, report researchers in JAMA.

A major study of children from three continents suggests that diabetic ketoacidosis remains unacceptably high among those newly identified with type 1 diabetes and shows few signs of improving.

Researchers provide further evidence to support two distinct type 1 diabetes endotypes characterized by a more or less aggressive autoimmune response and a younger or older age at onset.

A high BMI may contribute to the risk for progressing from single to multiple islet autoantibodies, especially in children who would otherwise be at relatively low risk, show findings from TrialNet.

Implementing a nursing protocol that includes point-of-care testing at triage reduces the time to diabetic ketoacidosis diagnosis and the number of unnecessary intravenous placements in the pediatric emergency department, say researchers.

Researchers report that women’s educational attainment is strongly associated with the glycated hemoglobin levels of their children with type 1 diabetes.

Factors associated with poor glycemic control in children with type 1 diabetes generally vary according to the insulin regimen used, but family conflict over diabetes management universally impacts all insulin users, US researchers report.

Insulin pumps and multiple daily injections deliver similar glycemic control and safety profiles when allocated alongside education and support at the point of type 1 diabetes diagnosis, say researchers.

Children with type 1 diabetes are more likely than their non-diabetic peers to seek primary care for a number of specific conditions in the year before their diagnosis, which could aid detection before the onset of diabetic ketoacidosis, say researchers.

Type 1 diabetes has no significant impact on standardized test scores in mathematics and reading for children in grades 2 to 8, show results of a study of Danish public school children.

The effect of sleep duration on glucose regulation and cardiometabolic risk is becoming an increasingly high-profile issue. medwireNews takes a look at the latest evidence, which shows the gravity of the problem but also offers some solutions.

Insulin manipulation, the practice of deliberately under- or overdosing insulin, is strongly associated with psychiatric comorbidity in children and young adults with type 1 diabetes, Austrian research shows.

Patients with type 1 diabetes diagnosed before the age of 10 years have a higher risk for cardiovascular complications and a shorter life expectancy than those who develop the disease at an older age, study results published in The Lancet suggest.

The Flexible Lifestyles Empowering Change intervention has failed to improve glycated hemoglobin levels in a randomized trial involving adolescents with type 1 diabetes, despite improving some psychosocial outcomes.

Many parents underestimate their child’s risk for type 1 diabetes, and although accuracy improves following a positive autoantibody result, it subsequently declines with time, a survey of TEDDY participants shows.

Neither the rate of administration nor the sodium chloride content of replacement fluids given to children with diabetic ketoacidosis influences their neurologic outcomes, show the results of the PECARN DKA FLUID Study.

A study of type 1 diabetes patients voluntarily following a very-low-carbohydrate diet suggests that the approach could help to achieve excellent control of blood glucose levels.

As the utility and availability of devices surges, so too do patient expectations. Advisory Board member Katharine Barnard provides key consultation questions to help determine your patients’ greatest needs and obstacles.

Tully C et al. Curr Diab Rep 2016; 16: 85. doi: 10.1007/s11892-016-0779-6